EyeWire

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EyeWire
EyeWire-Logo-Blue.png
Studio Massachusetts Institute of Technology
Erstveröffent-
lichung
December 10, 2012
platform Web browser ( WebGL )
genre Citizen Science
medium Online at: www.eyewire.org
language English

EyeWire is an online game for citizen scientists to neurons in the retina to map. EyeWire was officially launched on December 10, 2012, and since then the number of players has grown to over 160,000 people from more than 145 countries. The game is a Massachusetts Institute of Technology project based on scanning electron microscope data provided by the Max Planck Institute for Medical Research .

Project

The idea for EyeWire came from a group of young neuroscientists and computer scientists at MIT, led by Sebastian Seung. They implemented the game design, the data infrastructure and analysis algorithms as well as the support of the community conceptually and practically. EyeWire was originally supported by the Gatsby Charitable Foundation , the Howard Hughes Medical Institute, and the Max Planck Society . The project is currently receiving financial support from the National Institutes of Health .

aims

The goals of EyeWire are to identify certain cell types within the known classes of retinal cells and to determine the three-dimensional connections between the neurons in the retina.

  • The first immediate goal is to reconstruct the three-dimensional shapes of retinal neurons from two-dimensional images.
  • The second goal is to identify the synapses in order to clarify the connections between the associated neurons.
  • The main goal is to determine the relationship between these neurons and their known activity.

EyeWire is part of a larger project called WiredDifferently , the aim of which is to show that the pattern of neuron connections, or the connectome, is unique in each person. A connectome is the term used to describe the entirety of the connections in the nervous system of a living being. Mapping this is the current research subject of the Human Connectome Project . Similar brain mapping projects are the EU's Human Brain Project and the US Brain Activity Map Project .

Course of the game

Before the game can begin, every new player receives an introduction in which the course of the game is explained in a practical way. The 2D scans of the mouse retina to be measured are stacked on top of one another within a 3D cube. The player is assigned a die and helps the artificial intelligence to mark the course of the neurons. By scrolling back and forth between the scans within the cube, he can view or mark the course of the neurons.

From this, the program calculates the 3D course of the neurons. When the player is done with the selection, the result is sent to the server. There, the artificial intelligence calculates the final course of neurons with the help of 5 to 25 identical cubes that have already been viewed by other players. After completing this sighting, the player receives points depending on the quality of his markings, which are noted in a highscore list. There are daily, weekly and monthly high score lists in which the players can compete.

Web links

Commons : EyeWire  - collection of images, videos and audio files

Individual evidence

  1. About EyeWire, A Game to Map the Brain . Retrieved February 21, 2015.
  2. About << EyeWire . Retrieved September 23, 2013.
  3. EyeWire Wiki: E2198 . Archived from the original on September 27, 2013. Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved September 23, 2013. @1@ 2Template: Webachiv / IABot / wiki.eyewire.org
  4. Wired Differently . Retrieved September 23, 2013.
  5. EyeWire Wiki . Retrieved May 2, 2017.
  6. wired.com: A Videogame That Recruits Players to Map the Brain from August 2, 2013.