F-53B

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Structural formula
Structural formula of F-53B
General
Surname F-53B
other names
  • Potassium 2 - [(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl) oxy] -1,1,2,2-tetrafluoroethanesulfonate
  • 8: 2-Cl-PFESA
Molecular formula C 8 ClF 16 KO 4 S
External identifiers / databases
CAS number 73606-19-6
ChemSpider 21442077
Wikidata Q17321574
properties
Molar mass 570.67 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

F-53B is the potassium salt of a perhalosulfonic acid and belongs to the group of per- and polyfluorinated alkyl compounds (PFAS).

use

F-53B has been used as an anti-fogging agent (mist suppressor) in Chinese electroplating technology for chrome plating since the 1970s . Compared to F-53 , which is fully fluorinated, there are price advantages in the synthesis. In water treatment, it behaves similarly to the anion of perfluorooctane sulfonic acid (PFOS). PFOS salts have also been used since 1982.

Hazard and risk assessment

F-53B has a similar strong binding affinity to the liver fatty acid binding protein as PFOS, which is bioaccumulative and was included in the Stockholm Convention . In addition, F-53B has at least as much toxicity as PFOS.

See also

Individual evidence

  1. ↑ Fangfang Chen, Shanshan Yin, Barry C. Kelly, Weiping Liu: Chlorinated Polyfluoroalkyl Ether Sulfonic Acids in Matched Maternal, Cord, and Placenta Samples: A Study of Transplacental Transfer. In: Environmental Science & Technology . 51 (11), 2017, pp. 6387-6394, doi : 10.1021 / acs.est.6b06049 .
  2. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  3. ↑ a b c d Siwen Wang, Jun Huang, Yang Yang, Yamei Hui, Yuxi Ge, Thorjørn Larssen, Gang Yu, Shubo Deng, Bin Wang, Christopher Harman: First Report of a Chinese PFOS Alternative Overlooked for 30 Years: Its Toxicity, Persistence, and Presence in the Environment. In: Environmental Science & Technology. 47 (18), 2013, pp. 10163-10170, doi : 10.1021 / es401525n .
  4. ↑ a b Weixiao Cheng, Carla A. Ng: Predicting Relative Protein Affinity of Novel Per- and Polyfluoroalkyl Substances (PFASs) by An Efficient Molecular Dynamics Approach. In: Environmental Science & Technology. 52 (14), 2018, pp. 7972-7980, doi : 10.1021 / acs.est.8b01268 .
  5. ↑ Nan Sheng, Ruina Cui, Jinghua Wang, Yong Guo, Jianshe Wang, Jiayin Dai: Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein. In: Archives of Toxicology . 92 (1), 2018, pp. 359-369, doi : 10.1007 / s00204-017-2055-1 .