Flualprazolam

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Structural formula
Structure of flualprazolam
General
Non-proprietary name Flualprazolam
other names
  • 6- (2-fluorophenyl) -1-methyl-8-chloro-4H- [1,2,4] triazolo [4,3-a] [1,4] benzodiazepine ( IUPAC )
  • 8-Chloro-6- (2-fluorophenyl) -1-methyl-4 H -benzo [f] [1,2,4] triazolo [4,3-a] [1,4] diazepine
Molecular formula C 17 H 12 ClFN 4
External identifiers / databases
CAS number 28910-91-0
PubChem 10359044
Wikidata Q62018618
Drug information
Drug class
properties
Molar mass 326.77 g · mol -1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Flualprazolam is a chemical compound from the benzodiazepine group , which was developed by Upjohn (now part of Pfizer ) in the 1970s , but was never marketed commercially. However, it has been offered on the Internet as a designer drug or legal high since around 2018 .

One can Flualprazolam than the 2'- fluoro - derivative of alprazolam see or as the fluorine instead of chlorine analogue of triazolam . Similar to this, it has a strong hypnotic , sedative and anxiolytic effect. The estimated equivalent dose of 10 mg diazepam is 0.25-0.5 mg.

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Patent US3987052 : 6-Phenyl-4H-s-triazolo [4,3-a] [1,4] benzodiazepines. Filed on October 29, 1969 , published on October 19, 1976 , Applicant: Upjohn Co, Inventor: Jackson B. Hester, Jr
  3. ↑ Waters, Manchester, Maskell, Haider, Haegeman: The use of a quantitative structure-activity relationship (QSAR) model to predict GABA-A receptor binding of newly emerging benzodiazepines . In: Science & Justice . 58, No. 3, 2017, pp. 219–225. PMID 29685303 .
  4. ↑ Jolanta B. Zawilska, Jakub Wojcieszak: An expanding world of new psychoactive substances-designer benzodiazepines . In: NEUTOX . 73, 2019, pp. 8-16. PMID 30802466 .
  5. ^ Bjoern Moosmann and Volker Auwärter: Designer Benzodiazepines: Another Class of New Psychoactive Substances . In: Handbook of Experimental Pharmacology . 252, 2018, pp. 383-410. PMID 30367253 .
  6. ↑ Emil Chetraru, Alice Ameline, Laurie Gheddar, Jean-Sébastien Raul, Pascal Kintz: Les designer benzodiazepines: qu'en sait-on aujourd'hui? Designer benzodiazepines: What do we know about them? . In: Toxicologie Analytique et Clinique . 30, No. 1, 2018. doi : 10.1016 / j.toxac.2017.12.001 .