Graciline

Structural formula
General
Surname	Graciline
other names	Barrelier; Taurine;
Molecular formula	C 15 H 20 O 3
External identifiers / databases
EC number	607-244-2
ECHA InfoCard	100.109.832
PubChem	211707
Wikidata	Q1541127
properties
Molar mass	248.3 g mol −1
Physical state	firmly
Melting point	118–119 ° C (from ethanol) ; 104–105 ° C (from hexane)
safety instructions
GHS hazard labeling ; no classification available
GHS hazard labeling ; no classification available
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Gracilin or Barrelierin is a sesquiterpene lactone that has been extracted from various species of the Artemisia genus , including Artemisia gracilescens and Artemisia taurica . It belongs to a group of sesquiterpene lactones, also known as eudesmanolides . Gracilin isolated from above-ground parts of Artemisia barrelieri showed an anti-inflammatory effect and reduced edema in the paws of rats caused by carrageenan .

Specific rotation angle:

[α] _{D, 19} = -120 ° (c = 5.0, ethanol)
[α] _{D, 20} = -108.6 ° (c = 0.019, ethanol)

Individual evidence

↑ NA Kechatova: sesquiterpenes lactones from "Artemisia Taurica". In: Chemistry of Natural Compounds. 4 (4), pp. 205-207 (1968).
↑ ^a ^b A. G. Safarova, SV Serkerov: New components of "Artemisia Taurica". In: Chemistry of Natural Compounds. 34 (2), pp. 244-245 (1998).
↑ ^a ^b ^c A. Zh. Turmukhambetov et al .: Gracilin - A new sesquiterpene lactone from "Artemisia gracilescens". In: Chemistry of Natural Compounds. 27 (3), pp. 292-295 (1991).
↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
^ MC Zafra-Polo, MA Blázquez: Anti-inflammatory activity of sesquiterpene lactones from "Artemisia barrelieri" in rats. In: Phytotherapy Research 5 (2), pp. 91-93 (1991).

[Kechatova-1] NA Kechatova: sesquiterpenes lactones from "Artemisia Taurica". In: Chemistry of Natural Compounds. 4 (4), pp. 205-207 (1968).

[SafarovaSerkerov-2] A. G. Safarova, SV Serkerov: New components of "Artemisia Taurica". In: Chemistry of Natural Compounds. 34 (2), pp. 244-245 (1998).

[Turmukhambetov-3] A. Zh. Turmukhambetov et al .: Gracilin - A new sesquiterpene lactone from "Artemisia gracilescens". In: Chemistry of Natural Compounds. 27 (3), pp. 292-295 (1991).

[NV-4] This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

[Zafra-5] MC Zafra-Polo, MA Blázquez: Anti-inflammatory activity of sesquiterpene lactones from "Artemisia barrelieri" in rats. In: Phytotherapy Research 5 (2), pp. 91-93 (1991).