Hemoglobinuria
| Classification according to ICD-10 | |
|---|---|
| R82.3 | Hemoglobinuria |
| ICD-10 online (WHO version 2019) | |
As hemoglobinuria excretion of is hemoglobin (red blood pigment) on the kidney called that if manifested an acute kidney failure can result.
Hemoglobinuria only occurs when, due to massive hemolysis, the binding capacity of the haptoglobin formed by the liver is exhausted or, if the haptoglobin concentration in the plasma is reduced due to liver damage, the tubular resorption capacity of the kidneys is simultaneously exhausted. When the hemoglobin is excreted in the urine, it turns dark.
The cause is acute, usually massive hemolysis , as can occur in various hemolytic anemias , transfusion incidents , malaria or autoantibody diseases (see cold agglutinins ).
However, only further clarification ( anamnesis , other laboratory parameters , symptoms , curve of the hemoglobin excretion: continuous or intermittent or paroxysmal ) in the given case can lead from the individual finding of hemoglobinuria to the diagnosis, which can ultimately also be:
- allergic hemoglobinuria
- toxic hemoglobinuria
- March hemoglobinuria , exercise hemoglobinuria
- intermittent hemoglobinuria
- Blackwater fever in malaria tropica after the use of Chinin
