HT-2 toxin

Structural formula
General
Surname	HT-2 toxin
Molecular formula	C 22 H 32 O 8
Brief description	colorless solid
External identifiers / databases
EC number	621-720-7
ECHA InfoCard	100.150.547
PubChem	10093830
ChemSpider	8269366
Wikidata	Q27896911
properties
Molar mass	424.48 g mol −1
Physical state	firmly
Melting point	151-152 ° C
solubility	soluble in dichloromethane , DMSO , ethanol and ethyl acetate ; bad in water;
safety instructions
GHS labeling of hazardous substances danger
H and P phrases	H: 300-310-315-319-330-335
	P: 260-264-280-284-302 + 350-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

HT-2 toxin is a mycotoxin (mold poison) from the trichothecenes group and a Fusarium toxin . It is one of the type A trichothecenes and arises as a metabolic product of fungi of the genus Fusarium .

Analytics

Like other trichothecenes, HT-2 toxin can be determined qualitatively and quantitatively in various test items after suitable sample preparation by coupling gas chromatography with mass spectrometry . The mass spectrum can also be found in the spectrum library of the NIST .

Web links

Joint FAO / WHO Expert Committee on Food Additives (JECFA), Monograph for T-2 and HT-2 toxins

Individual evidence

↑ ^a ^b ^c ^d data sheet from Fermentek for the HT-2 toxin
↑ ^a ^b Data sheet HT-2 toxin from Sigma-Aldrich , accessed on April 3, 2011 ( PDF ).
↑ Wanda M. Haschek, Colin G. Rousseaux, Matthew A. Wallig: Haschek and Rousseaux's Handbook of Toxicologic Pathology . Academic Press, 2013, ISBN 978-0-12-415765-1 , pp. 1208 ff . ( limited preview in Google Book search).
↑ Dongyou Liu: Manual of Security Sensitive Microbes and Toxins . CRC Press, 2014, ISBN 978-1-4665-5398-9 , pp. 547 ( limited preview in Google Book search).
↑ Melchert HU, Pabel E: Reliable identification and quantification of trichothecenes and other mycotoxins by electron impact and chemical ionization-gas chromatography-mass spectrometry, using an ion-trap system in the multiple mass spectrometry mode. Candidate reference method for complex matrices. , J Chromatogr A. 2004 Nov 12; 1056 (1-2): 195-199, PMID 15595550
↑ Entry on Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8- (3-methylbutanoate), (3α, 4β, 8α) - (mass spectrum, electron ionization). In: P. J. Linstrom, W. G. Mallard (Eds.): NIST Chemistry WebBook, NIST Standard Reference Database Number 69 . National Institute of Standards and Technology , Gaithersburg MD, accessed November 17, 2019.

[Fermentek-1] ta sheet from Fermentek for the HT-2 toxin

[Sigma-2] Data sheet HT-2 toxin from Sigma-Aldrich , accessed on April 3, 2011 ( PDF ).

[Wanda_M._Haschek,_Colin_G._Rousseaux,_Matthew_A._Wallig-3] Wanda M. Haschek, Colin G. Rousseaux, Matthew A. Wallig: Haschek and Rousseaux's Handbook of Toxicologic Pathology . Academic Press, 2013, ISBN 978-0-12-415765-1 , pp. 1208 ff . ( limited preview in Google Book search).

[Dongyou_Liu-4] Dongyou Liu: Manual of Security Sensitive Microbes and Toxins . CRC Press, 2014, ISBN 978-1-4665-5398-9 , pp. 547 ( limited preview in Google Book search).

[5] Melchert HU, Pabel E: Reliable identification and quantification of trichothecenes and other mycotoxins by electron impact and chemical ionization-gas chromatography-mass spectrometry, using an ion-trap system in the multiple mass spectrometry mode. Candidate reference method for complex matrices. , J Chromatogr A. 2004 Nov 12; 1056 (1-2): 195-199, PMID 15595550

[6] Entry on Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8- (3-methylbutanoate), (3α, 4β, 8α) - (mass spectrum, electron ionization). In: P. J. Linstrom, W. G. Mallard (Eds.): NIST Chemistry WebBook, NIST Standard Reference Database Number 69 . National Institute of Standards and Technology , Gaithersburg MD, accessed November 17, 2019.