Harry M. Rose
Harry Melvin Rose (born May 30, 1906 in Niles , Ohio - † November 4, 1986 in Meredith , New Hampshire ) was an American medical doctor ( microbiology , immunology ), known as one of the discoverers of rheumatoid factor (RF).
As a child, Rose developed polio , which led to paraplegia. As a student, he also developed pulmonary tuberculosis. He studied medicine at Cornell University Medical School with a degree in 1928 and an MD in 1932. In 1952 he became professor of microbiology and immunology at Columbia University . In 1977 he retired and practiced as a doctor for internal medicine until 1984.
Rose discovered rheumatoid factor independently from Erik Waaler (1940) through the accidental discovery of a laboratory assistant suffering from rheumatoid arthritis who used her own blood in a sheep blood cell test to investigate Q fever . She observed agglutination, which Ragan attributed to her arthritis history. Rose then undertook systematic series of tests with Charles Ragan in 1948, which corroborated his suspicions. A test developed afterwards was also named after Waaler and Rose.
In addition, he did research in virology, the mechanism of antibiotic action, and contributed to the development of flu vaccines. He was editor of the Journal of Immunology.
In 1959 he was one of the first winners of the Canada Gairdner International Award with Ragan . He also received the Gorgas Medal and the Squibb Award from the Infectious Disease Society. He was a fellow of the American College of Physicians .
Web links
Individual evidence
- ^ Obituary in the NY Times, Nov. 7, 1986
- ^ HM Rose, C. Ragan, E. Pearce, MO Lipman: Differential agglutination of normal and sensitized sheep erythrocytes by sera of patients with rheumatoid arthritis, Proc. Soc. Exp. Biolog. Med., Vol. 68, 1949, pp. 1-11
| personal data | |
|---|---|
| SURNAME | Rose, Harry M. |
| ALTERNATIVE NAMES | Rose, Harry Melvin |
| BRIEF DESCRIPTION | American medic |
| DATE OF BIRTH | May 30, 1906 |
| PLACE OF BIRTH | Niles , Ohio , United States |
| DATE OF DEATH | 4th November 1986 |
| Place of death | Meredith , New Hampshire , United States |