Horst Feldmann

Horst Wilhelm Albert Feldmann (born March 13, 1932 in Stettin ) is a German molecular biologist. Until 1997 he was a professor at the Adolf Butenandt Institute at the Ludwig Maximilians University in Munich .

Life

Horst Feldmann studied chemistry at the University of Cologne and completed his dissertation in 1962. From 1962 to 1967 he was a research assistant at the Institute for Genetics at the University of Cologne , headed by Max Delbrück . He completed his habilitation in 1968 at the Medical Faculty of the Ludwig Maximilians University in biochemistry .

Horst Feldmann conducted research in Cologne and Munich mainly on various aspects of the molecular biology of the yeast Saccharomyces cerevisiae : Yeast serves as an experimental model organism and is an ideal system for investigating cell architecture and fundamental cellular mechanisms. Yeast is a unicellular eukaryote . It grows in defined media and is suitable for mass production; it is accessible to all classical and molecular genetic techniques. Yeast is the first eukaryote whose full genome has been deciphered. Feldmann co-founded the Yeast Genome Project , which was completed in 1996 and published in Nature in 1997. Since then, yeast has served as a model system for functional analyzes and as an important reference for such studies on other organisms. Key Findings: (i) 40% of yeast and human genetic information is highly conserved; (ii) the yeast genome harbors several hundred genes whose related genes cause disease in humans. Genetically modified yeast cultures are u. a. used for the industrial production of biopharmaceuticals .

Feldmann was the founder and spokesman of the SFB 190 Mechanisms and Factors of Gene Activation of the German Research Foundation (funded from 1990 to 2001). From 1971 to 2007 he was involved in the organization of the International Spetses Summer Schools .

Joachim Hauber ( Heinrich Pette Institute for Experimental Virology and Immunology in Hamburg ) is one of his students . Feldmann lives in Bergkirchen .

Awards

1996 Diplome d'Honneur from FEBS

Web links

Feldmann's homepage with curriculum vitae and list of publications

literature

Horst Feldmann (Ed.): Yeast: Molecular and Cell Biology, 2nd Edition . 2nd Edition. Wiley-Blackwell, Weinheim 2012, ISBN 978-3-527-33252-6 .
Gregor Cicchetti, Vera Köster: H. Feldmann on the Oldest Domesticated Organism: Yeast . In: ChemViews . December 4, 2012, doi : 10.1002 / chemv.201200136 (interview with H. Feldmann).

Individual evidence

↑ Kürschner's German Scholarly Calendar, Feldmann
↑ Horst WA Feldmann: About methods of representation of some asymmetrical diaminodicarboxylic acids: Reactions on α-oximino-β-oxo-dicarboxylic acid esters and on α, β- unsaturated dicarboxylic acid esters . Cologne 1962, DNB 481165592 (dissertation).
^ S. Wenkel and U. Deichmann (eds.) Max Delbrück and Cologne: an early chapter of German molecular biology. World Scientific 2007, doi: 10.1142 / 9789812775818 .
^ Horst WA Feldmann: Investigations on the multiplicity of serine-specific transfer ribonucleic acids from yeast . Munich 1968, OCLC 796121393 (habilitation thesis).
^ Horst WA Feldmann: A Life with Yeast Molecular Biology . In: Vladmir P. Skulachev, Giorgio Semenza (Ed.): Comprehensive Biochemistry (= Stories of success: personal recollections XI ). tape 46 . Elsevier, Amsterdam 2008, ISBN 978-0-444-53225-1 , doi : 10.1016 / S0069-8032 (08) 00004-1 .
Jump up ↑ A. Goffeau, BG Barrell, H. Bussey, RW Davis, B. Dujon, H. Feldmann, F. Galibert, JD Hoheisel, C. Jacq, M. Johnston, EJ Louis, HW Mewes, Y. Murakami, P. Philippsen, H. Tettelin, SG Oliver: Life with 6000 genes. In: Science . Volume 274, 1996, pp. 563-567, PMID 8849441 .
^ Nature, Volume 387, Number 6632S, 1997 Yeast Directory
↑ SFB 190: Mechanisms and factors of gene activation. German Research Foundation , archived from the original on May 18, 2015 ; Retrieved February 20, 2017 .
^ The Spetses Summer Schools. (PDF; 1.9 MB) In: uni-muenchen.de. Retrieved February 20, 2017 .

personal data
SURNAME	Feldmann, Horst
ALTERNATIVE NAMES	Feldmann, Horst Wilhelm Albert (full name)
BRIEF DESCRIPTION	German molecular biologist
DATE OF BIRTH	March 13, 1932
PLACE OF BIRTH	Szczecin

[1] Kürschner's German Scholarly Calendar, Feldmann

[2] Horst WA Feldmann: About methods of representation of some asymmetrical diaminodicarboxylic acids: Reactions on α-oximino-β-oxo-dicarboxylic acid esters and on α, β- unsaturated dicarboxylic acid esters . Cologne 1962, DNB 481165592 (dissertation).

[3] S. Wenkel and U. Deichmann (eds.) Max Delbrück and Cologne: an early chapter of German molecular biology. World Scientific 2007, doi: 10.1142 / 9789812775818 .

[4] Horst WA Feldmann: Investigations on the multiplicity of serine-specific transfer ribonucleic acids from yeast . Munich 1968, OCLC 796121393 (habilitation thesis).

[5] Horst WA Feldmann: A Life with Yeast Molecular Biology . In: Vladmir P. Skulachev, Giorgio Semenza (Ed.): Comprehensive Biochemistry (= Stories of success: personal recollections XI ). tape 46 . Elsevier, Amsterdam 2008, ISBN 978-0-444-53225-1 , doi : 10.1016 / S0069-8032 (08) 00004-1 .

[6] Jump up ↑ A. Goffeau, BG Barrell, H. Bussey, RW Davis, B. Dujon, H. Feldmann, F. Galibert, JD Hoheisel, C. Jacq, M. Johnston, EJ Louis, HW Mewes, Y. Murakami, P. Philippsen, H. Tettelin, SG Oliver: Life with 6000 genes. In: Science . Volume 274, 1996, pp. 563-567, PMID 8849441 .

[7] Nature, Volume 387, Number 6632S, 1997 Yeast Directory

[8] SFB 190: Mechanisms and factors of gene activation. German Research Foundation , archived from the original on May 18, 2015 ; Retrieved February 20, 2017 .

[9] The Spetses Summer Schools. (PDF; 1.9 MB) In: uni-muenchen.de. Retrieved February 20, 2017 .