Iberiotoxin

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Potassium channel toxin alpha-KTx 1.3
other names

Iberiotoxin, IbTx

Mass / length primary structure 37 amino acids , 4,254 Da
Identifier
External IDs

Iberiotoxin (synonym Kaliumkanaltoxin alpha-KTx 1.3 , IbTx ) is a toxin from the red Indian scorpion Mesobuthus tamulus .

properties

Iberiotoxin is a protein and scorpion toxin . Iberiotoxin binds and inhibits calcium- activated potassium channels of the type maxi-K ( KCa1.1 / KCNMA1 ). Iberiotoxin is structurally related to charybdotoxin a , charybdotoxin b , limbatus toxin and also to noxious toxin , margatoxin and tityus toxin Kα .

Individual evidence

  1. ^ Hervé Rochat: Animal Toxins. Springer Science & Business Media, 2000, ISBN 978-3-764-35983-6 , p. 184.