Institute for Molecular Pathogenesis

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Institute for Molecular Pathogenesis
Category: Departmental research facility
Carrier: Friedrich Loeffler Institute
Legal form of the carrier: Higher federal authority
Seat of the wearer: Greifswald , Riems Island
Facility location: Jena
Type of research: Departmental research
Subjects: Natural sciences
Areas of expertise: Veterinary medicine
Basic funding: Federal Government ( BMELV )
Management: Christian crowd
Homepage: www.fli.de
BW

The Institute for Molecular Pathogenesis (IMP) is a research facility of the Federal Republic of Germany which, as a branch in Jena, is part of the legally independent higher federal authority Friedrich-Loeffler-Institut . The institute primarily conducts departmental research for the Federal Ministry of Food, Agriculture and Consumer Protection . The research tasks of the IMP are in the field of veterinary medicine .

history

The Institute for Molecular Pathogenesis and the Jena-based Institute for Bacterial Infections and Zoonoses (IBIZ) go back to the "Institute for Bacterial Animal Disease Research" (ITSF) of the former German Academy of Agricultural Sciences in the GDR, which was founded on July 1, 1954 . At the end of the 1950s, the construction of new buildings for the ITSF began at its current location in Jena- Zwätze . One of the strengths of the ITSF was to bring the representatives of the various disciplines (veterinarians, chemists, physicists, biologists, farmers) together to work on the research tasks.

The political turnaround and German reunification also represented a decisive turning point for the Jena Institute. On the basis of a recommendation by the Science Council , the institution became part of the Institute for Veterinary Medicine (Robert von Ostertag -Institute) of the Federal Health Office . After the dissolution of the Federal Health Office, the institute in Jena was part of the newly founded Federal Institute for Consumer Health Protection and Veterinary Medicine (BgVV) from 1994 onwards . This was dissolved in November 2002.

Even after the incorporation in November 2002 as the Jena site into the “Federal Research Center for Virus Diseases of Animals” (BFAV), it was possible to continue significant parts of the traditional fields of work. In addition, research projects oriented towards current problems were increasingly tackled and new laboratory methods were incorporated.

The Federal Research Institute BFAV was renamed in 2004 to “Friedrich-Loeffler-Institut” (FLI) with the additional designation “Federal Research Institute for Animal Health”.

research

The IMP was fundamentally reorganized in 2005. The main topics of the research and reference activities are now mycobacteria and Campylobacter infections.

The research activities of the working groups in the IMP focus on scientific studies on the interactions between infectious agents and host organisms (pathogen-host interactions) in the development and spread of various infectious diseases in animals. This applies not only to the above-mentioned key issues, but also to other animal diseases with zoonotic potential or great economic relevance ( e.g. salmonella , chlamydia , mycoplasma or viral infections). The basis of the institute's scientific competence is formed by the working groups active in the fields of immunology (focus on poultry), pathology / histology and clinical physiology / pathophysiology , with the inclusion of a solid animal experimental basis.

The results obtained serve to combat these diseases with the aim of creating healthy animal populations as a basis for the production of high-quality and harmless food.

Reference laboratories

The National Reference Laboratories (NRL) perform extensive sovereign tasks in the sense of monitoring and improving the diagnosis of notifiable animal diseases , notifiable animal diseases and zoonoses .

The following national reference laboratories are assigned to the Institute for Molecular Pathogenesis:

National Reference Laboratory for Tuberculosis
The Tuberculosis is an infectious disease caused by pathogens of the genus Mycobacterium is caused. It is mutually transferable between humans and animals and therefore belongs to the group of zoonoses .
National Reference Laboratory for Paratuberculosis
The paratuberculosis , also called "Johnsche disease", is a by Mycobacterium paratuberculosis induced chronic inflammatory bowel disease mainly in ruminants.
National reference laboratory for intoxicating fire
Rauschbrand is an acute and highly febrile, sometimes endemic animal disease. The causative agent of the disease is the bacterium Clostridium chauvoei .
National Reference Laboratory for Vibrion Disease
The Vibrionenseuche of cattle is a by infertility characterized, early embryonic mortality and abortion, venereal disease. It is caused by the Campylobacter fetus ssp. venerealis.
National Reference Laboratory for Maling Disease
The dourine disease (Dourine) is a chronic or acute venereal infectious disease of equines. The pathogen Trypanosoma equiperdum is transmitted directly from animal to animal during mating and cannot be transmitted to humans.

See also

Web links

Coordinates: 50 ° 57 ′ 17 "  N , 11 ° 36 ′ 57.7"  E