Jean-Marie Ghuysen

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Jean-Marie Ghuysen (born January 26, 1925 in Blégny - Trembleur , † August 31, 2004 in Liège ) was a Belgian microbiologist .

Ghuysen was able to explain the mode of action of the β-lactam antibiotics , which inhibit the synthesis of the bacterial cell wall. He described the peptidoglycan layer there and the biochemistry of the penicillin-binding proteins (PBP, now known as transpeptidases ).

Life

Ghuysen's father was a pharmacist and mayor in Blégny - Trembleur . Jean-Marie Ghuysen studied pharmacology and chemistry at the University of Liège . During the war he supported the Resistance as a messenger and bomb maker. In 1947 he obtained a degree in pharmacology, in 1948 in chemistry and in 1951 a Ph.D. from Victor Desreux. in physical chemistry . Ghuysen then got a job at Labaz , but in 1958 he moved to the University of Liège, where he received an extraordinary professorship in 1966 and a full professorship in 1969. In 1990 Ghuysen retired , but was still in charge of the protein engineering center there until 1995 .

Ghuysen was married, his wife Jeanine (née Defourny, 1925–2003) died a year before him. The couple had three children.

Awards (selection)

literature

Individual evidence

  1. Awards and Prize Lectures at the Society for General Microbiology (sgm.ac.uk) ( Memento from September 5, 2012 in the Internet Archive )
  2. Jean-Marie Ghuysen PhD at the Gairdner Foundation (gairdner.org); Retrieved November 11, 2012
  3. Summary List of UNESCO Prizes (PDF, 95 kB, status 1998) at UNESCO (unesco.org); Retrieved November 11, 2012
  4. ^ Admin: Prof. Jean-Marie Ghuysen. In: consejoculturalmundial.org. November 12, 1997, accessed April 17, 2018 .
  5. Facts Sheet (PDF, 506 kB) at Bristol-Myers Squibb (bms.com); Retrieved February 20, 2016