Kjell Kleppe

Kjell Kleppe (1985)

Kjell Kleppe ( December 9, 1934 - June 18, 1988 ) was a Norwegian biochemist and molecular biologist . He is considered one of the pioneers of genetic engineering in Norway and was involved in the experiments to duplication of DNA by Gobind Khorana involved the late 1960s and early 1970s.

Kjell Kleppe studied from 1955 to 1958 at the University of Oslo and then as a Fulbright scholar at the University of Nebraska , where he received his doctorate in enzymology in 1963 . As a postdoctoral fellow , he was in the Biochemistry Department at the University of Cambridge and the Norsk Hydro Institute for Cancer Research in Oslo . From 1966 he was assistant (Amanuensis), from 1970 lecturer and from 1976 professor of biochemistry at the University of Bergen . With Curt Endresen he founded the joint laboratory for biotechnology (Felleslaboratorium for bioteknologi, FLB, from 1997 part of the new institute for molecular biology in Bergen) in Norway and was its first director. He was instrumental in ensuring that the university received a high technology center (HIB) in 1990.

Kleppe was a postdoctoral fellow with Gobind Khorana at the University of Wisconsin from 1968 to 1970 and was also part of Khorana's group when Khorana went to MIT. Research with Khorana on the amplification of DNA with DNA polymerases formed a basis for the polymerase chain reaction concept developed by Kary Mullis in the early 1980s , for which Mullis was awarded the 1993 Nobel Prize in Chemistry .

He was a member of EMBO and the Norwegian Academy of Sciences (1984).

In his honor there is the annual Kjell Kleppe lecture in Bergen.

Web links

Professor Kjell Kleppe (1934–1988) - Biochemist, genetic engineer and pioneer , Department of Molecular Biology, University of Bergen

Individual evidence

^ K. Kleppe, E. Ohtsuka, R. Kleppe, I. Molineux, HG Khorana: Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases . In: J Mol Biol . tape 56 , no. 2 , March 14, 1971, p. 341-361 , doi : 10.1016 / 0022-2836 (71) 90469-4 , PMID 4927950 (English).

personal data
SURNAME	Kleppe, Kjell
BRIEF DESCRIPTION	Norwegian biochemist
DATE OF BIRTH	December 9, 1934
DATE OF DEATH	June 18, 1988

[1] K. Kleppe, E. Ohtsuka, R. Kleppe, I. Molineux, HG Khorana: Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases . In: J Mol Biol . tape 56 , no. 2 , March 14, 1971, p. 341-361 , doi : 10.1016 / 0022-2836 (71) 90469-4 , PMID 4927950 (English).