Siegfried Pharma Chemicals Minden
| Siegfried PharmaChemischem Minden GmbH | |
|---|---|
| legal form | GmbH |
| founding | 1935 (entry in the commercial register as Chemische Werke Minden GmbH ) 2000 (spin-off from Knoll AG as BASF Pharmachemikalischer GmbH & Co. KG ) |
| Seat | Minden , Germany |
| management | Marco Millies (Managing Director) |
| Number of employees | around 340 |
| Branch | Pharma |
The Siegfried Pharma Chemicals Minden GmbH is a chemical plant in North Rhine-Westphalia Minden , Germany . As a subsidiary of Siegfried Holding AG from Zofingen , Switzerland , it produces chemicals for the pharmaceutical industry .
The history of pharmaceutical production in Minden goes back to 1939. Knoll AG , founded in Ludwigshafen am Rhein in 1886, registered Chemische Werke Minden GmbH in the commercial register in 1935 and started production at the new location around four years later. The subsidiary was later integrated into the parent company and the Minden location was operated as a Knoll branch until 2000. In August 2000, the BASF Group, to which Knoll AG now belonged, decided to outsource the production of pharmaceutical chemicals as BASF PharmaChemischem GmbH & Co. KG . The subsidiary that was created in this way initially belonged entirely to the BASF Group and from 2010 onwards was part of the “Nutrition & Health” division. In 2015, it was sold to today's parent company with a corresponding change in the company name.
history
prehistory
The Knoll AG goes to the chemist Albert Knoll , back. He developed a new process for chemically converting morphine into codeine . The active ingredient was needed to treat coughs and pain, as it had a similar effect to the previously widely used morphine, but without its problematic side effects, such as the high risk of addiction. Knoll AG , which he founded in Ludwigshafen am Rhein, began production as early as 1886.
In 1934 and 1935, the Reich authorities responsible for medical depots held out the prospect of larger contracts. A commission from the Army Sanitary Inspector , however, considered the previous Ludwigshafen location to be unfavorable. It was believed that the Knoll AG production facility was too close to the border with France, and it was feared that French troops could disrupt production and thus the supply of important medicines. The commission called for a production facility to be set up deeper inland. In the commemorative publication published for the 100th anniversary of Knoll AG , it is reported that a medical officer stabbed his circle near Minden by chance when he tried to narrow down the area considered safe on a map of Germany during a meeting. A company-internal memo under the subject “Safeguarding Knoll's production” had received the note “Minden - not suitable” in 1934. Minden had a lot to offer as a location, above all a connection to the important Cologne - Berlin railway line, as well as to the water lines Weser and Mittelland Canal .
Chemische Werke Minden GmbH and Knoll AG
In 1935, Chemische Werke Minden GmbH was entered in the commercial register with a share capital of 300,000 Reichsmarks, a year later a plot of 20,000 square meters was purchased and a further 27,000 square meters were added in 1939. Production in a newly built factory on Karlsstrasse began in 1939. At the insistence of the Wehrmacht , tannalbin and cardiazol were initially produced, followed by Dilaudid , Dicodid and Paracodin by 1941 . The number of employees rose to 183 in 1943. In the same year, production of the alkaloid papaverine began in Minden .
After the Second World War, the plant was expanded with a sewage treatment plant and a new administration building. In the 1950s, the company's management increasingly changed the focus of production away from finished, salable drugs to their precursors and intermediates.
In September 1975, BASF AG from Ludwigshafen took over the majority of the shares in Knoll AG and continued to run it as a subsidiary. In the anniversary year of 1986, the Minden site had around 600 employees, produced around 150 individual products and, according to the company, operated the world's largest plants for the production of ephedrine and synthetic caffeine . In addition, the synthesis of papaverine, started in 1943, had meanwhile developed into a larger area for the production of the intermediate product veratryl cyanide. The substance was used to produce Verapamil , the active ingredient in Isoptin , a very successful drug from the parent company Knoll AG for use in heart disease. Minden also supplied mandelic acid , tyramine , cyanoacetic acid and methylurea, among others .
The Albert Knoll Prize , donated by Knoll AG, is awarded annually for outstanding work in the field of internal medicine .
BASF Pharma Chemicals GmbH & Co. KG
As part of a restructuring of BASF , the Minden plant was spun off from Knoll AG in June 2000 with BASF PharmaChemischem GmbH & Co. KG . In this new, wholly-owned subsidiary, the group bundled both BASF’s own production of active pharmaceutical ingredients as well as the production of active pharmaceutical ingredients that was previously managed by Knoll AG . Your company headquarters was in Ludwigshafen am Rhein, at the location of the parent company. Minden was then subordinate to the “BASF Fine Chemicals” division. As a result of the spin-off, the Minden plant remained in the BASF Group when, in 2001, the entire remaining pharmaceutical division , managed by Knoll AG , was sold to the American Abbott Laboratories . “BASF Fine Chemicals” was reorganized in 2008 and the division around BASF PharmaChmikalischer renamed “Pharma Ingredients & Services”. As of August 2010, the business unit and the Minden plant were part of the newly created BASF division “Nutrition & Health”.
In April 2012, BASF announced that it would withdraw its production of "Kolliphor TGPS", a water-soluble vitamin E derivative (vitamin E polyethylene glycol succinate), from Kankakee , Illinois in the USA and relocate it to Minden. This gave Minden a new central production facility.
In 2012, around 350 people were employed at the site. In the same year, 21 apprentices were trained in the professions of chemical technician, laboratory technician and chemical production specialist. On February 14, 2012, Marco Millies took over the management of the plant from Werner Biffar, the long-time managing director.
Siegfried PharmaChemischem Minden GmbH
In spring 2015 it was announced that BASF will sell its active pharmaceutical ingredients business to Siegfried Holding by autumn . In addition to the production sites in Evionnaz , Switzerland and St. Vulbas in France, the Minden plant was also affected by the transaction .
On October 15, 2015, the new owner changed the name to Siegfried PharmaChemischem Minden GmbH and at the same time relocated the company's headquarters from Ludwigshafen am Rhein to Minden in Westphalia. At the beginning of 2017, 14 trainees were employed in Minden.
Products
80 individual fabrics are produced here. Mainly chemicals of the active ingredient groups ephedrine and purines for the pharmaceutical industry and caffeine for the food industry as well as basic materials for in-vitro diagnostics are produced.
Web links
- BASF celebrates 75 years of the Minden site accessed in September 2010
Individual evidence
- ↑ Facts & Figures on the Siegfried AG website , accessed on March 22, 2017
- ^ Knoll Aktiengesellschaft. BASF Group (Ed.): Many facts - some riddles . In: 100 Years in the Service of Health 1886–1986, Ludwigshafen am Rhein 1986. p. 95
- ^ Knoll Aktiengesellschaft. BASF Group (Ed.): A stately branch begins to grow in Minden . In: 100 Years in the Service of Health 1886–1986, Ludwigshafen am Rhein 1986. p. 95
- ^ City of Minden (Hrsg.): Minden, witnesses and testimonials of its urban development . Minden 1979, p. 115.
- ↑ a b BASF celebrates the anniversary of the Minden site , BASF press release , September 15, 2010, on: Press portal pressrelations , accessed on April 6, 2017
- ^ Knoll Aktiengesellschaft. BASF Group (Ed.): A stately branch begins to grow in Minden . In: 100 Years in the Service of Health 1886–1986, Ludwigshafen am Rhein 1986. P. 94
- ^ Albert Knoll Prize 1992. In: Internal medicine. Volume 19, No. 3, 1992, p. VII.
- ↑ BASF: Production of Kolliphor TPGS relocated to Minden . In: Finanz.net , April 30, 2012, accessed May 30, 2017
- ↑ Positive impulses for the Minden location . In: Mindener Tageblatt , May 12, 2012
- ↑ The best team, interview with managing director PD Dr. Marco Millies . In: Mindener Tageblatt , October 20, 2012, accessed on January 8, 2013
- ↑ BASF sells parts of the pharmaceutical business . In: Handelsblatt , May 7, 2015, accessed on January 30, 2016
- ↑ Achim Post: Mayor Michael Jäcke and Member of the Bundestag Achim Post visiting the Siegfried company in Minden , accessed on May 30, 2017.
Coordinates: 52 ° 17 ′ 54 ″ N , 8 ° 56 ′ 30 ″ E