Cresidines

The cresidines form a group of substances derived from anisole  (methoxybenzene), toluene  (methylbenzene) and aniline  (aminobenzene). The structure consists of a benzene ring with attached methoxy  (–OCH ₃ ), methyl  (–CH ₃ ) and amino  (–NH ₂ ) groups as substituents . Their different arrangement results in ten constitutional isomers with the empirical formula C ₈ H ₁₁ NO and a molar mass of 137.18 g / mol.

If one proceeds from the disubstituted parent compounds, then one can regard the cresidines as methyl derivatives of anisidines , as methoxy derivatives of toluidines or as amino derivatives of methoxy-substituted cresols (=  cresyl methyl ether ). The naming followed the last variant. Just as the anise idine from ordinary registered anise oil or Phenet idine of Phenet ol derived, was carried out in a manner analogous to the naming for Kres idine from Kres ol (nitrogen-containing derivatives of cresols).

The most important cresidins are:

• 3-methoxy- p -toluidine, o -cresidine
• 4- methoxy- o -toluidine, m -residine
• 6- methoxy- m -toluidine, p -residine

Cresidines
Trunk connection
	2-methyl anisole ( o -cresyl methyl ether)
Structural formula
Surname	3-amino-1-methoxy- 2-methylbenzene	4-amino-1-methoxy- 2-methylbenzene	5-amino-1-methoxy- 2-methylbenzene 3-methoxy- p -toluidine o -Cresidine	6-amino-1-methoxy- 2-methylbenzene
CAS number	19500-02-8	136-90-3	16452-01-0
ECHA InfoCard	100.202.591	100.213.247	100.036.803
PubChem
Brief description	Solid	Solid	Solid

Cresidines
Trunk connection
	3-methyl anisole ( m -cresyl methyl ether)
Structural formula
Surname	2-amino-1-methoxy- 3-methylbenzene	4-amino-1-methoxy- 3-methylbenzene 4-methoxy- o- toluidine m -residine	5-amino-1-methoxy- 3-methylbenzene	6-amino-1-methoxy- 3-methylbenzene
CAS number	50868-73-0	102-50-1	66584-31-4	39538-68-6
ECHA InfoCard	100.156.956	100.002.761		100,049,526
PubChem	459249	7610	44533	170219
Brief description	harmful liquid	difficult to ignite, black to brown liquid		harmful solid

Cresidines
Trunk connection
	4-methyl anisole ( p -cresyl methyl ether)
Structural formula
Surname	2-amino-1-methoxy- 4-methylbenzene 6-methoxy- m- toluidine p -residine	3-amino-1-methoxy- 4-methylbenzene
CAS number	120-71-8	50868-72-9
ECHA InfoCard	100.004.018	100.051.634
PubChem	8445	99500
Brief description	hardly flammable, black solid	harmful solid

Individual evidence

1. ↑ Data sheet 3-Methoxy-2-methylaniline from Sigma-Aldrich , accessed on December 27, 2019 ( PDF ).
2. ↑ Data sheet 4-Methoxy-3-methylaniline from Sigma-Aldrich , accessed on December 27, 2019 ( PDF ).
3. ↑ Entry for CAS no. 16452-01-0 in the GESTIS substance database of the IFA , accessed on December 27, 2019(JavaScript required) .
4. ↑ Data sheet 2-Methoxy-6-methylaniline from Sigma-Aldrich , accessed on December 27, 2019 ( PDF ).
5. ↑ Entry for CAS no. 102-50-1 in the GESTIS substance database of the IFA , accessed on December 27, 2019(JavaScript required) .
6. ↑ Data sheet 2-Methoxy-4-methylaniline from Sigma-Aldrich , accessed on December 27, 2019 ( PDF ).
7. ↑ Entry on 6-methoxy-m-toluidine in the GESTIS substance database of the IFA , accessed on December 27, 2019(JavaScript required) .
8. ↑ Data sheet 5-Methoxy-2-methylaniline from Sigma-Aldrich , accessed on December 27, 2019 ( PDF ).

Web links

Commons : Kresidine  - Collection of pictures, videos and audio files