Lothar Schweigerer

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Lothar Schweigerer (2018)

Lothar Schweigerer (born September 6, 1953 in Morbach / Hunsrück) is a German pediatrician, oncologist and cancer researcher . He held the chair for paediatrics at the University Medical Center Göttingen and is the chief physician of the clinic for child and adolescent medicine at the Helios Clinic Berlin-Buch .

Life

Schweigerer attended the Nikolaus-von Kues high school in Bernkastel-Kues , studied human medicine at the Justus-Liebig University in Gießen from 1973 to 1980 and passed his medical state examination there in 1980. He then worked at the Rudolf-Buchheim Institute for Pharmacology in Giessen as a research assistant, where he received his doctorate summa cum laude on the immunological function of endorphins in 1984 . With a grant from the Max Kade Foundation, he worked as a post-doctoral research assistant in Denis Gospodarowicz's laboratory at the Cancer Research Institute of the University of California San Francisco(USA) with the mechanisms of tumor angiogenesis . Napoleone Ferrara , who discovered the vascular endothelial growth factor, co-authored several papers . In 1987 Schweigerer returned to Germany and worked in the laboratory of Manfred Schwab, the discoverer of the MYCN gene , at the German Cancer Research Center in Heidelberg on the development and progression mechanisms of neuroblastoma .

In 1987, Schweigerer established his own research group on the subject of tumor angiogenesis and at the same time began his training as a pediatrician at the Clinic for Pediatric and Adolescent Medicine at the Ruprecht-Karls-Universität Heidelberg . After his qualification as a specialist in pediatric and adolescent medicine (1993) and his habilitation (1995), he was a senior physician at the Clinics for Pediatric and Adolescent Medicine at the Philipps University in Marburg and the University Clinic in Essen from 1994 to 1997 and 1997 to 2002 active.

Schweigerer received several appeals, including calls to the C3 professor of Pediatric Hematology and Oncology at the University Hospital Carl Gustav Carus Dresden (1999), the "Chair ( Chair ) of Hematology and Oncology" of the Great Ormond Street Hospital for Children at the University College London ( UK) (2001) and the C4 professorship for paediatrics with a focus on hematology and oncology at the Georg-August University of Göttingen (2001). From 2002 to 2006 he held the chair for paediatrics and was chief physician at the clinic for child and adolescent medicine with a focus on hematology and oncology and from 2003 to 2005 managing director of the clinic for child and adolescent medicine at the Georg-August University of Göttingen .

In 2006 he accepted an offer to head the clinic for pediatric and adolescent medicine at the Helios-Klinikum Berlin-Buch in the immediate vicinity of the Berlin-Buch research campus .

Schweigerer pursues the concept of "all-round care" for sick children and their families and has established a parental home, a parent oasis and a guest kindergarten at the clinic to care for healthy siblings. All offers are free of charge and are financed by the Mcdonald's Kinderhilfestiftung , the Ein Herz für Kinder foundation and the Eduard-Winter-Kinderstiftung. For the sick children he established many entertainment offers , including performances in the clinic's own theater (e.g. with the Konzerthaus Berlin ) and activities such as clown consultation, making music or works in the clinic's own music studio or workshop.

Schweigerer is the author of over 90 original scientific papers, a founding member of the EDU College of Medicine, chairman of the ICKE in Buch eV association, president of the circle of friends of the Ronald McDonald family home in Berlin-Buch and the medical advisory board of the "Rote Nasen" association.

Awards

  • Young Investigator Award from the European Society for Medical Oncology (1988)
  • Science Prize of the Kind Philipp Foundation for Leukemia Research (1991)
  • Gerhard Domagk Prize for clinical and experimental cancer research (1995)
  • Dr. Heinz and Helene Adam Foundation for Research into Blood and Lymph Vascular Diseases (1996).

Original scientific papers (selection)

  • With Sucharit Bhakdi and Hansjörg Teschemacher: Specific non-opiate binding sites for human beta-endorphin on the terminal complex of human complement . In: Nature 296 (1982), p. 572 PMID 7070501
  • With Gera Neufeld, Jeff Friedman, Judith Abraham, John Fiddes and Denis Gospodarowicz: Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth . In: Nature 325 (1987), p. 257 PMID 2433585
  • With Gera Neufeld, Ayalew Mergia, Judith Abraham, John Fiddes and Denis Gospodarowicz: Basic fibroblast growth factor in human rhabdomyosarcoma cells: implications for the proliferation and neovascularization of myoblast-derived tumors . In: PNAS 84 (1987), p. 842 PMID 2433691
  • With Napoleone Ferrara , Gera Neufeld, Richard Mitchell and Denis Gospodarowicz: Pituitary follicular cells produce basic fibroblast growth factor . In: PNAS 84 (1987), p. 5773 PMID 2441393
  • With Gera Neufeld and Denis Gospodarowicz: Basic fibroblast growth factor as a growth inhibitor for cultured human tumor cells . In: J. Clin. Invest. 80 (1987), p. 1516 PMID 2824563
  • With Theodore Fotsis, Michael Pepper, Herman Adlercreutz , Gudrun Fleischmann, Tapio Hase, and Roberto Montesano: Genistein, a dietary-derived inhibitor of in vitro angiogenesis . In: PNAS 90 (1993), p. 2690 PMID 7681986
  • With Theodore Fotsis, Youming Zhang, Michael Pepper, Hermann Adlercreutz, Tapio Hase, Peter Nawroth and Roberto Montesano: The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumor growth . In: Nature 368 (1994), p. 237 PMID 7511798
  • With Matthias Wilm, Andrej Shevchenko, Tony Houthaeve, Stephen Breit, Theodore Fotsis and Matthias Mann : Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry . In: Nature 379 (1996), p. 466 PMID 8559255

Individual evidence

  1. ^ Rudolf Buchheim Institute. Retrieved July 2, 2018 .
  2. ↑ JBC. Retrieved June 27, 2018 .
  3. ^ D Gospodarowicz's research works | Cancer Research Institute, New York City and other places. Retrieved July 2, 2018 .
  4. ↑ Manfred Schwab | German Cancer Research Center, Heidelberg | DKFZ | Tumor Genetics. Retrieved July 2, 2018 .
  5. ↑ Tumor angiogenesis. Retrieved June 27, 2018 .
  6. ^ Activity in Marburg. Retrieved June 27, 2018 .
  7. ↑ Activity eating. Retrieved June 27, 2018 .
  8. ↑ Vocations. Retrieved June 27, 2018 .
  9. ↑ CV Schweigerer. Retrieved June 27, 2018 .
  10. ^ Helios: web site Helios-Klinikum Berlin-Buch. In: Helios web site. Retrieved June 27, 2018 .
  11. ↑ Family-friendly care. Retrieved June 27, 2018 .
  12. ^ Child in hospital I Helios Klinikum Berlin-Buch. Accessed June 27, 2018 (German).
  13. ↑ pubmeddev: Schweigerer - PubMed - NCBI. Retrieved June 27, 2018 .
  14. ^ EDU. Retrieved June 27, 2018 .
  15. ↑ http://www.icke-in-buch.de. Retrieved June 27, 2018 .
  16. ↑ Prof. Dr. Lothar Schweigerer - McDonald's Children's Aid. (No longer available online.) Archived from the original on June 27, 2018 ; accessed on June 27, 2018 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.mcdonalds-kinderhilfe.org
  17. ↑ Committees. Retrieved September 7, 2018 .
  18. ↑ Kind-Philipp Prize Winner. Retrieved June 27, 2018 .

Web links

personal data
SURNAME Schweigerer, Lothar
BRIEF DESCRIPTION German pediatrician, oncologist
DATE OF BIRTH September 6, 1953
PLACE OF BIRTH Morbach