As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .
Meclonazepam [ ( S ) -3-methylclonazepam ] is a chemical compound from the group of benzodiazepines , which was developed by Hoffmann-La Roche in the 1970s . It is similar in structure to clonazepam . This benzodiazepine, which, in addition to its sedative and anxiolytic effects, is also effective in high doses against schistosomiasis , was never commercially available. It is now offered on the Internet as a designer drug.
↑ Patent US4031078A : Benzodiazepine derivatives. Registered on October 14, 1975 , published June 21, 1977 , applicant: Hoffmann-La Rouche Inc, inventor: Andre Szente.
^ Witzel S., Arnold U., Nagel G., Vettin J., Wilck A., Paul T .: Schistosomiasis. In: Pschyrembel Clinical Dictionary. Walter de Gruyter, 2007, ISBN 978-3-11-018534-8 (2160 pages).
↑ Laura M. Huppertz, Philippe Bisel, Folker Westphal, Florian Franz, Volker Auwärter, Bjoern Moosmann: Characterization of the four designer benzodiazepines clonazepam, deschloroetizolam, flubromazolam, and meclonazepam, and identification of their in vitro metabolites. Ed .: Forensic Toxicology April 33, 2015, ISSN 1860-8973 , p.8 , doi : 10.1007 / s11419-015-0277-6 (English, researchgate.net [PDF; accessed on March 16, 2019]).
↑ Pettersson Bergstrand M, Helander A, Hansson T, Beck O: Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays . In: Drug Test Anal . 9, No. 4, 2016, pp. 640-645. doi : 10.1002 / dta.2003 . PMID 27366870 .
↑ Kieran R. Manchester, Peter D. Maskell, Laura Waters: Experimental versus theoretical log D 7.4 , pK a and plasma protein binding values for benzodiazepines appearing as new psychoactive substances . In: Drug Testing and Analysis . 10, No. 8, 2018, ISSN 1942-7611 , pp. 1258-1269. doi : 10.1002 / dta.2387 . PMID 29582576 .
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