Melvin Greaves

Sir Melvin "Mel" F. Greaves (born September 12, 1941 ) is a British oncologist .

Life and research

Greaves went to school in Norwich and studied medicine at University College London , majoring in immunology . In 1968 Melvin was awarded a Dr. med. PhD. As a post-doctoral student, Greaves was at the Karolinska Institute near Stockholm from 1968 to 1969 . After this time he conducted research at the Immunology Department of the National Institute for Medical Research in Mill Hill, London ; subsequently, from 1972 for the Imperial Cancer Research Fund, and from 1976 as head of the laboratory for immunology at Lincoln's Inn Fields in London. From 1984 to 2003 he was Director of the Leukemia Research Center at the Institute of Cancer Research in London. Since 1985 Greaves has been Professor of Cell Biology at the University of London and Head of the Department of Hemato-Oncology at the Cancer Research Institute in London.

Greaves, who has been involved in cancer research since the 1970s, researched the development of leukemia in children and found evidence of prenatal genesis. Since the malignant prenatal genetic changes lead to leukemia in only around 1% of children, according to Greaves further factors must be added after birth, whereby Greaves pursues, among other things, the hypothesis of sufficient exposure to antigens, which is necessary for the development of adequate immune defense , and the lack of which can trigger a specifically abnormal immune reaction to common infections ( delayed infection hypothesis ).

According to Greaves, almost all cancer cases are multi- causal and usually also have causes that are subject to individual control.

Honors

1977 Paul Martini Prize in Göttingen
1981 Peter Debye Prize
1986 Honorary Member of the Royal College of Physicians
1988 King Faisal Prize
1999 Gold Medal from the British Society of Hematology
2001 José Carreras Award
2003 Fellow of the Royal Society , Fellow of the Academy of Medical Sciences in London
2017 Royal Medal of the Royal Society
2019 Knight Bachelor

Fonts

Cancer of the stowaway of evolution , Springer 2002 (Cancer - the evolutionary legacy, Oxford University Press 2000)
Infection, immune responses and the etiology of childhood leukaemia , Nature Reviews Cancer , Volume 6, 2006, pp. 193-203

Web links

Individual evidence

↑ Mori, Colman, Xiao, Ford, Healy, Donaldson, Howa, Navarrete, Greaves Chromosome translocations and covered leukemic clones are generated during normal fetal development , Proc. Nat. Acad. Sci., Vol. 99, 2002, p. 8242
↑ My view about all cancers, including children's cancer, is that you get the disease because of a combination of circumstances - genetics, exposures, dietary factors, energy balance - and sheer bad luck , Interview with Angela Grosse 2008

personal data
SURNAME	Greaves, Melvin
ALTERNATIVE NAMES	Greaves, Melvyn F.
BRIEF DESCRIPTION	British oncologist
DATE OF BIRTH	September 12, 1941

[1] Mori, Colman, Xiao, Ford, Healy, Donaldson, Howa, Navarrete, Greaves Chromosome translocations and covered leukemic clones are generated during normal fetal development , Proc. Nat. Acad. Sci., Vol. 99, 2002, p. 8242

[2] My view about all cancers, including children's cancer, is that you get the disease because of a combination of circumstances - genetics, exposures, dietary factors, energy balance - and sheer bad luck , Interview with Angela Grosse 2008