Microcytic anemia
| Classification according to ICD-10 | |
|---|---|
| D50.8 | Microcytic anemia |
| ICD-10 online (WHO version 2019) | |
Microcytic anemia is a collective term for any type of anemia that is characterized by small erythrocytes . The normal mean single erythrocyte volume (abbreviated to MCVin blood count results) is 76-100 fL . With smaller cells (<76 fL) it is called microcytic and with large cells (> 100 fL) it is called macrocytic. In microcytic anemia, the erythrocytes are mostly also hypochromic , which means that the erythrocytes are paler than usual. This can be determined by the mean corpuscular hemoglobin , the amount of hemoglobin per cell; the normal value is 27-32 picograms (pg). Similar is the mean corpuscular hemoglobin concentration (MCHC), at which the amount of hemoglobin per volume of erythrocytes is usually around 320-360 g / L or 32-36 g / dL. Typically, anemia in this category is therefore described as “microcytic, hypochromic anemia”.
species
Typical types of microcytic anemia are:
- childhood
- Iron deficiency anemia , by far the most common type of anemia and, in general, especially microcytic anemia
- Thalassemia
- Adulthood
- Bleeding
- Iron deficiency anemia
- Sideroblastic anemia , congenital or acquired
- Chronic disease anemia, although it is more likely to cause normochromic , normocytic anemia. Microcytic anemia has been reported by Weng et al. discussed.
- Lead poisoning
- Vitamin B6 deficiency
Other types believed to be a "typical" cause of normochromic anemia or microcytic anemia must also be considered. Since there can be two or more causes of anemia, this “typical” view becomes greatly skewed.
See also
Individual evidence
- ↑ A. Iolascon, L. De Falco, C. Beaumont: Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis . In: Haematologica . tape 94 , no. 3 , January 2009, p. 395-408 , doi : 10.3324 / haematol.13619 , PMID 19181781 , PMC 2649346 (free full text).
- ^ A b C. H. Weng, JB Chen, J. Wang, CC Wu, Y. Yu, TH Lin: Surgically Curable Non-Iron Deficiency Microcytic Anemia: Castleman's Disease . In: Oncology . tape 34 , no. 8-9 , 2011, pp. 456-458 , doi : 10.1159 / 000331283 , PMID 21934347 .
