Orosomucoid
| Orosomucoid | ||
|---|---|---|
| Mass / length primary structure | 180 amino acids | |
| Identifier | ||
| Gene name (s) | ORM1 | |
| External IDs | ||
Orosomucoid or acid alpha1-glycoprotein (AGP) is an early acute phase protein that is primarily produced in the liver cells . It modifies the adhesion of the platelets and suppresses the immune response . It also promotes the growth of fibroblasts . The normal value in human blood serum is 0.55–1.4 g / l. Together with haptoglobin , orosomucoid is a marker for hemolysis . Orosomucoid is also used to control therapy in Crohn's disease and various tumors.
literature
- Friedrich W. Tiller, Birgit Stein: Laboratory diagnostic practice . ecomed-Storck, 3rd edition 2013, ISBN 978-3-609-16473-1 , p. 414.