Oxalobacter formigenes

Oxalobacter formigenes
Systematics
Department : Proteobacteria Class : Betaproteobacteria Order : Burkholderiales Family : Oxalobacteraceae Genre : Oxalobacter Type : Oxalobacter formigenes
Scientific name
Oxalobacter formigenes
Allison et al. 1985

Oxalobacter formigenes is an oxalate- degrading anaerobic bacterium which occurs colonized in the large intestine of numerous vertebrates, including humans. O. formigenes lives in a symbiosis with humans. Quinolone , a broad-spectrum antibiotic, kills O. formigenes in the gastrointestinal tract . When a person lacks this bacterium, the primary source of the enzyme oxalyl-CoA decarboxylase , which breaks down calcium oxalate , is missing. Such a deficiency can promote the formation of kidney stones containing calcium oxalate.

Individual evidence

1. ↑ DW Kaufman, JP Kelly, GC Curhan, TE Anderson, SP Dretler, GM Preminger, DR Cave: Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stones. In: Journal of the American Society of Nephrology: JASN. Volume 19, number 6, June 2008, pp. 1197-1203, doi : 10.1681 / ASN.2007101058 , PMID 18322162 , PMC 2396938 (free full text).
2. ↑ Nina Dudek: Bacteria against stones. In: Focus Online . July 14, 2009, accessed October 14, 2018 .