Paracoccidioides brasiliensis

Paracoccidioides brasiliensis
	Paracoccidioides brasiliensis
Systematics
Department :	Ascomycota mushrooms
Subdivision :	Real ascent mushrooms (Pezizomycotina)
Class :	Eurotiomycetes
Subclass :	Eurotiomycetidae
Order :	Onygenales
Type :	Paracoccidioides brasiliensis
Scientific name
	Paracoccidioides brasiliensis
	( Splend. ) FP Almeida

Paracoccidioides brasiliensis ( Syn. Blastomyces brasiliensis ) is a dimorphic, primary pathogenic fungus from the group of the Fungi imperfecti (also imperfect fungi , Deuteromycetes ). This fungus is the causative agent of South American blastomycosis , which results in a multitude of different skin deformations and ulcers, especially on the mucous membranes and lymph nodes .

The morphology of Paracoccidioides brasiliensis is temperature-dependent, in the yeast phase at 37 ° C and in the mycelial phase up to 30 ° C (slow growth). These are 10–40 μm, double-contoured, spherical cells with multiple sprout cells on blood agar.

Microscopic evidence

Sprout cells in the unstained native preparation from pus , sputum or other exudates, also as lymph node homogenates after lightening with 10% sodium hydroxide solution .

literature

Curt Hunnius, Hermann Ammon : Hunnius - Pharmaceutical Dictionary . de Gruyter, Berlin 2004, ISBN 978-3-11-017475-5

Individual evidence

↑ Chen D, Janganan TK, Chen G, Marques ER, Kress MR, Goldman GH et al .: The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis. . In: Mol Microbiol . 65, No. 3, 2007, pp. 761-779. PMID 17635191 .

[pmid17635191-1] Chen D, Janganan TK, Chen G, Marques ER, Kress MR, Goldman GH et al .: The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis. . In: Mol Microbiol . 65, No. 3, 2007, pp. 761-779. PMID 17635191 .