Peter Scheiffele

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Peter Scheiffele (2011)

Peter Scheiffele (born December 21, 1969 in Berlin ) is a German neurobiologist and professor at the Biozentrum of the University of Basel , Switzerland .

Life

Peter Scheiffele studied biochemistry at the Free University of Berlin . In 1998 he received his doctorate at the European Molecular Biology Laboratory in Heidelberg and then worked as a postdoc at the University of California, Berkeley and University of California, San Francisco . In 2001 he became an assistant professor in the Department of Physiology & Cellular Biophysics at Columbia University , New York, doing research in the field of neurobiology. Peter Scheiffele has been Professor of Cell and Developmental Biology at the Biozentrum of the University of Basel since 2008.

Act

Scheiffele researches the mechanisms of the formation of neural networks in the central nervous system . In particular, he studies the formation of synapses . Peter Scheiffele discovered an important role for the neuronal adhesion molecules neuroligin and neurexin in the formation of synapses. He showed that Neuroligin enters into a trans-synaptic connection with the presynaptic surface receptor neurexin and is important for the organization of the components of the synapse membrane. His work on the formation and dissolution of neuronal synapses also led to insights into neuronal diseases such as autism and their treatment options.

Awards

  • 2002 Alfred P. Sloan Research Fellow
  • 2002 Searle Scholar Award
  • 2004 John Merck Scholar Award
  • 2005 Simons Foundation Young Investigator Award
  • 2013 elected member of the European Molecular Biology Organization (EMBO)
  • 2014 Robert Bing Prize 2014
  • 2016: ERC Advanced Grant

Publications (selection)

Complete list of publications

  • Peter Scheiffele, Johan Peränen and Kai Simons: N-glycans as apical sorting signals in epithelial cells. In: Nature . Volume 378, 1995, pp. 96-98. PMID 7477300
  • Peter Scheiffele, Jinhong Fan, Jenny Choih, Richard Fetter and Tito A. Serafini: Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. In: Cell . Volume 101, 2000, pp. 657-669. PMID 10892652
  • Ben Chih, Holly Engelman, Peter Scheiffele: Control of excitatory and inhibitory synapse formation by neuroligins. In: Science . Volume 307, 2005, pp. 1324-1328. PMID 15681343
  • Takatoshi Iijima, Karen Wu, Harald Witte, Yoko Hanno-Iijima, Timo Glatter, Stéphane Richard, Peter Scheiffele: SAM68 regulates neuronal activity-dependent alternative splicing of Neurexin-1. In: Cell. Volume 147, No. 7, 2011, pp. 1601-1614. PMID 22196734
  • Stephane Baudouin, Julien Gaudias, Stefan Gerharz, Laetitia Hatstatt, Keiku Zhou, Pradeep Punnakkal, P; Kenji F Tanaka, Will Spooren, Rene Hen, Chris I. De Zeeuw, Kaspar Vogt, Peter Scheiffele: Shared Synaptic Pathophysiology in Syndromic and Non-syndromic Rodent Models of Autism. In: Science. Volume 338, No. 6103, 2012, pp. 128-132. PMID 22983708

Web links

Individual evidence

  1. ↑ Curriculum Vitae, Robert Bing Prize Winner 2014 ( Memento of the original from September 28, 2014 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. samw.ch, accessed on June 23, 2014. @1@ 2Template: Webachiv / IABot / www.samw.ch
  2. ↑ Disruption of neural circuits in autism is reversible from psychorienachrichten.de, accessed on June 23, 2014
  3. ↑ Autism: changes in the brain cancel. derstandard.at, accessed June 23, 2014
  4. ^ 2002 Alfred P. Sloan Research Fellow sloan.org, accessed June 23, 2014
  5. ↑ 2002 Searle Scholar Award searlescholars.net, accessed June 23, 2014
  6. ↑ 2004 John Merck Scholar Award jmfund.org, accessed June 23, 2014
  7. ↑ EMBO Fellows ( Memento of the original from March 4, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. embo.org, accessed June 23, 2014 @1@ 2Template: Webachiv / IABot / fellowsnet.embo.org
  8. ↑ Robert Bing Prize goes to a brain researcher from Basel and a Geneva-based brain researcher basellandschaftlichezeitung.ch, accessed June 23, 2014
  9. ↑ EU funding in the millions for four researchers at the University of Basel unibas.ch, accessed on May 30, 2016.
  10. ↑ Complete list of publications Biozentrum.unibas.ch. Retrieved June 23, 2014
personal data
SURNAME Scheiffele, Peter
BRIEF DESCRIPTION German neurobiologist and university professor
DATE OF BIRTH December 21, 1969
PLACE OF BIRTH Berlin