Plastochromanol-8

Structural formula
General
Surname	Plastochromanol-8
other names	γ-tocopherol-9
Molecular formula	C 53 H 82 O 2
External identifiers / databases
PubChem	6438333
Wikidata	Q15632864
properties
Molar mass	751.2 g mol −1
safety instructions
GHS hazard labeling ; no classification available
GHS hazard labeling ; no classification available
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Plastochromal-8 (abbreviation: PC-8 ) is a natural, lipophilic antioxidant , which was found in high amounts in flaxseed . So far, however, PC-8 is still largely unexplored.

Occurrence

Soybeans , latex, rapeseed and corn contain significant amounts of PC-8. This was demonstrated above all in the chloroplasts of the plants mentioned above, increasingly during the growth phase. Traces of PC-8 were also in grape seed oil , mustard oil , poppy seed oil , cotton seed oil and pumpkin seed oil discovered.

structure

The structure of the PC-8 is very similar to the structure of tocotrienols , coenzyme Q10 and vitamin K . PC-8 is made up of a chromanol-6 ring, which has an isoprenoid side chain. This side chain in turn contains 8 isoprene units .

properties

The physiological functions of PC-8 have so far been little explored. It is known to have an antioxidant effect which is more pronounced compared to α- tocopherol . Among the prenyl lipids, PC-8 has been shown to be the most versatile antioxidant in inhibiting lipid peroxidation.

Individual evidence

↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
↑ ^a ^b ^c ^d ^e D. Olejnik, M. Gogolewski, M. Nogala-Kałucka: Isolation and some properties of plastochromanol-8 . In: Food / nutrition . tape 41 , no. 2 , 1997, p. 101-104 , doi : 10.1002 / food.19970410209 .
^ ^A ^b ^c E. Sondergaard, H. Dam: Occurrence of a plastochromanol in linseed oil . In: Acta chemica Scandinavica . tape 21 , no. 9 , 1967, p. 2582 , PMID 5631056 .
↑ Jolanta Gruszka, Anna Pawlak, Jerzy Kruk: Tocochromanols, plastoquinol, and other biological prenyllipids as singlet oxygen quenchers-determination of singlet oxygen quenching rate constants and oxidation products . In: Free Radical Biology and Medicine . tape 45 , no. 6 , September 15, 2008, p. 920-928 , doi : 10.1016 / j.freeradbiomed.2008.06.025 , PMID 18634868 .
↑ Beatrycze Nowicka, Jolanta Gruszka, Jerzy Kruk: Function of plastochromanol and other biological prenyllipids in the inhibition of lipid peroxidation-A comparative study in model systems . In: Biochimica et Biophysica Acta . tape 1828 , no. 2 , February 2013, p. 233-240 , doi : 10.1016 / j.bbamem.2012.08.018 , PMID 22959712 .

[NV-1] This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

[Oljenik-2] D. Olejnik, M. Gogolewski, M. Nogala-Kałucka: Isolation and some properties of plastochromanol-8 . In: Food / nutrition . tape 41 , no. 2 , 1997, p. 101-104 , doi : 10.1002 / food.19970410209 .

[Leerbeck-3] A ^b ^c E. Sondergaard, H. Dam: Occurrence of a plastochromanol in linseed oil . In: Acta chemica Scandinavica . tape 21 , no. 9 , 1967, p. 2582 , PMID 5631056 .

[Gruszka-4] Jolanta Gruszka, Anna Pawlak, Jerzy Kruk: Tocochromanols, plastoquinol, and other biological prenyllipids as singlet oxygen quenchers-determination of singlet oxygen quenching rate constants and oxidation products . In: Free Radical Biology and Medicine . tape 45 , no. 6 , September 15, 2008, p. 920-928 , doi : 10.1016 / j.freeradbiomed.2008.06.025 , PMID 18634868 .

[Nowicka-5] Beatrycze Nowicka, Jolanta Gruszka, Jerzy Kruk: Function of plastochromanol and other biological prenyllipids in the inhibition of lipid peroxidation-A comparative study in model systems . In: Biochimica et Biophysica Acta . tape 1828 , no. 2 , February 2013, p. 233-240 , doi : 10.1016 / j.bbamem.2012.08.018 , PMID 22959712 .