Price-Jones curve
The Price-Jones curve describes the distribution of the diameter of the red blood cells (erythrocytes) in a blood sample and is normally very similar to a normally distributed Gaussian curve with the maximum at around 7.5 micrometers. However, the Price-Jones curve has a closed domain of definition. It therefore has no huge and no negative values for the diameter, as would be the case with a Gaussian distribution. It is named after the British hematologist and pathologist Cecil Price-Jones .
A right shift of the mean value of this curve is called macrocytosis , a left shift is called microcytosis . Erythrocytes that are abnormally large are called macrocytes and abnormally small ones are called microcytes. If the concentration is too high and balanced, the Price-Jones curve is flattened and one speaks of anisocytosis . The mean erythrocyte volume is represented by the MCV value .
literature
- Gerhard Thews , Peter Vaupel : Vegetative Physiology. Springer-Verlag, 2013, ISBN 978-3-662-10747-8 , p. 39 ( limited preview in Google book search).