Hyperglobulinaemica purpura
| Classification according to ICD-10 | |
|---|---|
| C88.0 | Macroglobulinaemia Waldenström |
| D89.0 | Polyclonal hypergammaglobulinaemia |
| ICD-10 online (WHO version 2019) | |
The purpura hyperglobulinaemica or Waldenstrom's disease (after January Gosta Waldenstrom ) is an acquired coagulopathy ( bleeding diathesis ), by the blood vessels starts. It is characterized by massive hypergammaglobulinaemia , i. That is, there is an excessive amount of gamma globulins ( antibodies ) in the patient's blood.
Secondary hyperglobulinaemica purpura is usually the result of a plasmacytoma , a rheumatic disease or Sjogren's syndrome .
From a laboratory point of view, the parameters of platelet count , platelet function and plasmatic coagulation parameters are unchanged; H. normal. Thus there are no coagulopathies , thrombocytopathies or thrombocytopenias .
literature
- H. Dörken: Primary and secondary hyperglobulinaemica purpura. In: Acta Haematol. 1953; 10, pp. 340-349.