Stefan Laufer

Professor Stefan Laufer, 2019

Stefan Laufer (born December 16, 1959 in Steinheim ) is a German pharmacist and professor of pharmaceutical chemistry at the Eberhard Karls University of Tübingen .

Life

From 1980 Laufer studied pharmacy at the University of Regensburg . After the practical year, he passed the third state examination in 1985 and received his license to practice medicine in the same year . He then worked as a research assistant and doctoral candidate at the Chair of Pharmaceutical Chemistry at the University of Regensburg until 1988, where he was awarded the title “ 5-Aminoisoxazole. Synthesis and Cardiovascular Effect ” under the supervision of PD. Dr. Dannhardt summa cum laude doctorate .

After receiving his doctorate, he worked as a research assistant at the Institute for Pharmaceutical Chemistry and Biopharmacy at the Johann Wolfgang Goethe University in Frankfurt am Main until 1990 . He then moved to the pharmaceutical industry, initially as head of the drug research department and, from 1996, head of research and development and member of the management of Merckle GmbH. At the same time he had lectureships at the universities of Frankfurt and Mainz. In 1997 he was at the University of Mainz with the work: "A concept for the development of side effects of nonsteroidal anti-inflammatory drugs poor dual inhibitors of cyclooxygenase and 5-lipoxygenase" habilitation and received venia legendi for the subject Chemistry. Part-time qualifications include specialist pharmacist for pharmaceutical analysis (1989), specialist pharmacist for toxicology and ecology (1994) and the Advanced Management Program European, INSEAD, Fontainebleau (1998). Since the winter semester 1999/2000 he has held the chair for pharmaceutical chemistry at the Eberhard Karls University in Tübingen .

Since his appointment, Laufer has been conducting academic drug research with strong translational requirements. He developed three active ingredients up to the first use on humans (Licofelone, CBS-3595, Skepinone-L).

His research focuses on inflammation, autoimmunity and cancer with the molecular targets of eicosanoid modulators and protein kinases. For translation purposes, he founded the inter-faculty center for pharmacogenomics and drug research in Tübingen / Stuttgart together with the Robert Bosch Foundation in 2005, where he was spokesperson from 2011 to 2019 and is still a member of the management committee. He has also been a member of the Center for Personalized Medicine since 2016 and co-founder of the Tübingen Center for Academic Drug Discovery & Development (TüCAD ₂ ) in 2015 , which has been a platform as part of the University of Tübingen's Excellence Strategy since 2017.

As a professor for pharmaceutical chemistry at the Eberhard-Karls-University in Tübingen, he has been active in various university committees since his appointment in 1999. He was dean from 2004 to 2006 and deputy from 2006 to 2015. Chairman of the University Council. In 2003 he introduced the “Pharmaceutical Sciences” diploma course in teaching, which was transferred to the “Pharmaceutical Sciences and Technologies” master’s course following the introduction of the Bologna reform.

In addition to his academic work, he was a member of the supervisory board of BioPro Baden-Württemberg GmbH and ProGen GmbH and is a co-founder of HepaRegeniX GmbH and CAIR Biosciences GmbH.

Activities abroad

Laufer is the founding dean of the German University of Cairo (GUC), which is the first German private university abroad to train around 400 pharmacists and biotechnologists every year.

Since 2005 he has been director of the Baden-Württemberg Brazil Center. He has been a member of the Brazilian Academy of Sciences (Academia Brasileira de Ciências) and a member of the scientific advisory board of the INCT-INOFAR (Instituto Nacional de Ciência e Tecnologia de Fármacos e Medicamentos) and Visiting Guest Professor at the URFJ in Rio de Janeiro since 2014.

Memberships

Laufer has long been involved in the German Pharmaceutical Society (DPhG). He was President from 2016 to 2019 and Vice President of the University from 2012 to 2015. Since 2002 he has headed the regional group Südwürttemberg-Hohenzollern and currently also the regional group Baden-Württemberg. In addition, he has been on the board of the Pharmaceutical and Medicinal Chemistry department since 2008, also in the joint department with the Society of German Chemists (GDCh). He is also a member of the Austrian Pharmaceutical Society (ÖPhG) and the American Chemical Society (MedChem Division).

Honors

1998: Call for a C-4 professorship for pharmaceutical chemistry at the University of Bonn (successor Prof. Nickel / Rücker), declined

1999: Call to a C-4 professorship for pharmaceutical chemistry at the University of Tübingen (successor to Prof. Roth), accepted

2003: Call for a C-4 professorship for pharmaceutical chemistry at the University of Freiburg (successor Prof. Nickel / Frahm), declined

2006: Phoenix Science Prize Pharmacy: "Synthesis and biological testing of purine derivatives as potential ATP - competitive kinase inhibitors"

2016: Teaching Award for Molecular Medicine (Advanced Molecular Oncology) as Best Lecturer

2017: Phoenix Science Prize Pharmacy: "Lung cancer: EGFR inhibitors with low nanomolar activity against a therapy resistant L858R / T790M / C797S mutant"

Literature / patents / publications

Laufer is the author of over 400 publications, author of 15 book chapters and is the inventor of over 40 patent families with over 300 national applications.

Individual evidence

1. ↑ DPhG: Prof. Dr. Stefan Laufer new DPhG President from 2016. Accessed on March 24, 2017 . 
2. ↑ Curriculum vitae | Pharmaceutical Chemistry | University of Tübingen. Retrieved March 24, 2017 . 
3. ↑ DPhG: Presentation of the candidate Prof. Dr. Stefan Laufer. Retrieved March 24, 2017 . 
4. ↑ DPhG: Presentation of the candidate Prof. Dr. Stefan Laufer. Retrieved March 24, 2017 . 
5. ↑ DPhG: Baden-Württemberg. Retrieved March 24, 2017 . 
6. ↑ Medicinal Chemistry | Society of German Chemists V. Accessed March 24, 2017 . 

Web links

• Chair page Stefan Laufer on the website of the Eberhard Karls University of Tübingen