Stephen PA Fodor

Stephen Philip Alan Fodor (* 1953 in Seattle , Washington ) is an American geneticist and entrepreneur. He is the founder of the biotechnology company Affymetrix and one of the pioneers of DNA chip technology .

Live and act

Fodor earned a bachelor's degree in biology and a master's degree in biochemistry from Washington State University . In 1985, he earned a Ph.D. from Princeton University. in chemistry . His dissertation was titled Ultraviolet Resonance Raman Spectroscopy of the Nucleic Acids . As a postdoctoral fellow he worked on a grant from the National Institutes of Health at the University of California, Berkeley , from where he was enlisted in 1989 at the Affymax Research Institute in Palo Alto , California . Here it was his task, together with Lubert Stryer and other arrays ( molecular biological examination systems) to miniaturize, which led to the development of microarrays and finally DNA chip technology . To improve the method, Affymax founded the subsidiary Affymetrix in 1993 , whose founder and director was Fodor.

The methods of Fodor and coworkers made large-scale genome analyzes such as the human genome project possible. The numerous applications of the method also include analyzes of the antibiotic resistance genes of microorganisms ( antibiotic resistance ) or the cancer genes of a tumor ( tumor suppressors , oncogenes ).

Awards (selection)

• 1990 Newcomb Cleveland Award from the American Association for the Advancement of Science (AAAS)
• 1998 Jacob Heskel Gabbay Award in Biotechnology and Medicine (with Patrick O. Brown )
• 2002 Takeda Foundation Award
• 2002 Economist Innovation Award for Nanotechnology
• 2002 Oxford Bioscience Award
• 2006 European Inventor Award
• 2009 member of the National Academy of Engineering
• 2016 Fellow of the American Association for the Advancement of Science

literature

• Tim Lenoir, Eric Giannella: The emergence and diffusion of DNA microarray technology . In: Journal of Biomedical Discovery and Collaboration . tape 1 , no. 1 , August 22, 2006, ISSN  1747-5333 , p. 11 , doi : 10.1186 / 1747-5333-1-11 , PMID 16925816 ( [1] ).

Web links

• Stephen PA Fodor, Ph.D. at Affymetrix (affymetrix.com)
• Stephen PA Fodor at DNA from the Beginning (dnaftb.org)
• Stephen PA Fodor Ph.D. at Bloomberg Businessweek (businessweek.com)

Individual evidence

1. ↑ SP Fodor, JL Read, MC Pirrung, L. Stryer , AT Lu, D. Solas: Light-directed, spatially addressable parallel chemical synthesis. In: Science. Volume 251, Number 4995, February 1991, pp. 767-773, ISSN  0036-8075 . PMID 1990438 .
2. ^ AAAS Newcomb Cleveland Prize, 1990. American Association for the Advancement of Science (aaas.org); accessed on January 1, 2014
3. ^ Past Winners - Gabbay Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved February 13, 2016 . 
4. ↑ Dr. Stephen PA Fodor at the National Academy of Engineering (nae.edu); accessed on January 1, 2014