Theodrenaline

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Structural formula
Structure of theodrenaline
General
Non-proprietary name Theodrenaline
other names
  • 7- (2 - {[2- (3,4-dihydroxyphenyl) -2-hydroxyethyl] amino} ethyl) -1,3-dimethyl-3,7-dihydro-1 H -purine-2,6-dione
Molecular formula C 17 H 21 N 5 O 5
External identifiers / databases
CAS number 13460-98-5
PubChem 71857
ChemSpider 64874
Wikidata Q7782198
Drug information
ATC code

C01 CA23

Drug class

Analeptic

Mechanism of action

α-adrenoceptor agonist

properties
Molar mass 375.38 g mol −1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
Pictogram unknown
H and P phrases H: ?
EUH: ?
P: ?
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Theodrenaline is a drug that is used in fixed combination with cafedrin for the parenteral treatment of a clinically relevant anesthesia-related drop in blood pressure , especially in emergency medicine .

In rapid-onset Theodrenalin mediated by α- adrenoceptors a vasoconstriction . Contractility , blood pressure , heart rate and, to a lesser extent , the cardiac output and the peripheral vascular resistance are increased.

Theodrenaline hydrochloride is used pharmaceutically .

Individual evidence

  1. ↑ G. Geisslinger et al .: Mutschler drug effects . 11th edition. WVG, Stuttgart 2019, p. 395.
  2. ↑ Product information Akrinor 200 mg / 2 ml + 10 mg / 2 ml injection solution (ratiopharm GmbH), as of August 2019.
  3. ↑ External identifiers or database links for theodrenaline hydrochloride: CAS number: 2572-61-4, EC number: 219-920-0, ECHA InfoCard: 100.018.110 , PubChem : 3083768 , ChemSpider : 2340923 , Wikidata : Q27266527 . Molecular formula: C 17 H 22 ClN 5 O 5 . Molar mass: 411.84 g mol −1 .