Thomas Scheibel

Thomas Scheibel (born April 16, 1969 in Regensburg ) is a German biochemist and university professor for biomaterials at the University of Bayreuth .

Thomas Scheibel

Life

He studied biology and biochemistry at the University of Regensburg , where he completed his diploma and doctoral theses at the Institute for Biophysics and Physical Biochemistry under the supervision of J. Buchner. He spent three years postdoctoral research at the University of Chicago with Susan Lindquist in the Department of Molecular Genetics and Cell Biology. Subsequently, from 2001 to 2007 he was working group leader at the Department of Biotechnology (Prof. Buchner) and has been involved in the production, characterization and technical use of protein materials since then. In November 2007 he was appointed to the University of Bayreuth to set up and head the new chair of Biomaterials at the Faculty of Applied Natural Sciences.

Since July 2012 he has been an editorial board member of the journal Scientific Reports (Nature Verlag), since October 2011 employee of the DIN standards committee "ISO-BIONIK", since February 2011 deputy. Chairman of the Advisory Board of AMSilk GmbH, since December 2010 Editorial Board Member of the magazine BioNanoScience (Springer Verlag), since April 2009 spokesman for the expert committee Bioinspired Materials and Bionics of the DGM, since October 2008 co-founder and advisor of AMSilk GmbH and since June 2008 advisory board of the competence network Biomimetics of the state of Baden-Württemberg.

Research priorities

The focus of Thomas Scheibel's interdisciplinary research activities is the characterization of biogenic materials, in particular structural proteins . The underlying peptides or proteins are produced biotechnologically, modified for technically relevant product requirements, and processed into future-oriented technical and medical-technical application forms. Natural materials often have optimized properties that far exceed those of artificially manufactured products. This makes proteins as a source of ideas for the development of innovative, bio-inspired materials for use e.g. B. in biomedicine or (nano) technology very attractive. The starting point of Thomas Scheibel's research is the understanding of the molecular interactions and assembly mechanisms of fibrous structural proteins of the natural models spider silk , insect silk ( lacewing ) or byssus threads from mussels . The aspects of self-assembly, mechanical behavior, the influence of environmental factors and post-treatment processes are of particular interest. The processing methods for proteins include processes for the production of fibers , fleeces , foils, particles, capsules or hydrogels .

Prizes and awards

• 2014: Member of the German Academy of Science and Engineering (acatech)
• 2013: DECHEMA Prize from the Max Buchner Research Foundation
• 2008: Prize of the Karl Heinz Beckurts Foundation
• 2007: Heinz Maier Leibnitz Medal
• 2007: Winner BMBF ideas competition "Bionics - innovation from nature"
• 2006: Innovation recognition award from the Bavarian Prime Minister
• 2006: Science4Life Venture Cup
• 2006: Winner BMBF bionics competition
• 2006: Winner Development Stage of the MBPW
• 2005: Promega Prize "Mainly Biology"
• 2004: Junior Scientist Award

Publications (selection)

• Scheibel, T .; Parthasarathy, R .; Sawicki, G .; Lin, X.-M .; Jaeger, H .; Lindquist, S. (2003). Conducting nanowires built by controlled self-assembly of amyloid fibers and selective metal deposition. Proc. Natl. Acad. Sci. USA 100, 4527-4532
• Huemmerich, D .; Helsen, CW; Oschmann, J .; Rudolph, R .; Scheibel, T. (2004). Primary structure elements of dragline silks and their contribution to protein solubility and assembly. Biochemistry 43, 13604-13612.
• Hardy, J., Roemer, L, Scheibel, T. (2008). Polymeric materials based on silk proteins. Polymer 49, 4309-4327
• Heim, M., Keerl, D., Scheibel, T. (2009). Spider Silk: From Soluble Protein to Extraordinary Fibers. Angew. Chem. Int. Ed., 48, 3584-3596
• Hagn, F., Eisoldt, L., Hardy, J., Vendrely, C., Coles, M., Scheibel, T., Kessler, H. (2010). A highly conserved spider silk domain acts as a molecular switch that controls fiber assembly Nature, 465, 239-242
• Eisoldt, L., Smith, A., Scheibel T. (2011). Spider silk: decoding the secrets of an ancient biopolymer material. Materials Today, 14, 80-86
• Claudia Blüm, Alfons Nichtl & Thomas Scheibel (2013). Spider silk capsules as protective reaction containers for enzymes. Advanced functional materials, 24, 763-768
• Michael Suhre, Melanie Gertz, Clemens Steegborn & Thomas Scheibel (2014). Structural and functional features of a collagen-binding matrix protein from the mussel byssus. Nature Communications , Article number 5: 3392
• Philip H. Zeplin, Nathalie C. Maksimovikj, Martin C. Jordan, Joachim Nickel, Gregor Lang, Axel H. Leimer, Lin Römer & Thomas Scheibel (2014). Spider silk coatings as a bioshield to reduce periprosthetic fibrous capsule formation. Advanced functional materials, 24, 2658-2666

Web links

• www.fiberlab.de

Individual evidence

1. ↑ http://portal.mytum.de/tum/honoratioren/HML/index_html
2. ↑ Archived copy ( Memento of the original from April 14, 2013 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. 
3. ↑ Archived copy ( memento of the original from October 8, 2012 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. 
4. ↑ Archived copy ( Memento of the original dated August 31, 2014 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. 
5. ↑ http://www.foerderland.de/419+M5f5a8e37fc2.0.html
6. ↑ http://fiberlab.de/homepages/tom/award2005.html
7. ↑ http://fiberlab.de/homepages/tom/JSA2004klein.jpg