Trachette Jackson

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Trachette Jackson (born July 24, 1972 in Monroe (Louisiana) ) is an American mathematician and university professor . She is Professor of Mathematics and Co-Director of the Mathematical Biology Research Group at the University of Michigan. Her research focuses on cancer tumor growth and tumor therapy, as well as cell-based mathematical approaches to simulate how blood vessels form during cancer growth.

Life and research

Jackson attended Mesa High School from 1987 to 1990 and spent her summers in the Math-Science Honors Program at Arizona State University, where she developed her passion for mathematics. In 1994 she received her bachelor 's degree in mathematics from Arizona State University . In 1996 she received her Masters degree and her PhD in 1998 with James Dickson Murray at the University of Washington . The dissertation was entitled "Mathematical Models in Two-Step Cancer Chemotherapy". She was a postdoctoral researcher at the Department of Mathematics and Applications at the University of Minnesota and from 1999 to 2000 she was a postdoctoral fellow with John Hope Franklin at the Center for Mathematics and Computing in the Life Sciences and Medicine at Duke University . From 2000 to 2003, she was an assistant professor of mathematics at the University of Michigan . In 2003 she was promoted to associate. In 2006, she was named co-principal investigator of the University of Michigan’s National Science Foundation (NSF) funded SUBMERGE program (providing experience in the biology and mathematics research group). In 2008, she became a full professor in the Michigan Department of Mathematics. She is co-founder and co-director of the Mathematics Biology Research Group (MBRG). The main focus of her research in mathematical oncology is the combination of mathematical modeling and in vivo tumor vascularization to gain a deeper understanding of tumor growth and the vascular structure of the molecular, cellular and tissue levels. She has published numerous articles on mathematical oncology, and in 2008 she was the senior editor for the academic journal Cancer Research. She is married to Patrick Nelson, with whom she has two sons.

Awards (selection)

  • Medallion of Merit Award, Arizona State University
  • 2003: Sloan Research Fellowship (after Kathleen Adebola Okikiolu the second African American woman)
  • 2005: James S. McDonnell 21st Century Scientist Award
  • 2010: lackwell Tapia Prize
  • 2011: Imes-Moore Award * 2012: Elizabeth Caroline Crosby Award * 2014: DAPCEP Real McCoy Award
  • 2017: Fellow of the Association for Women in Mathematics

Memberships

  • Society for Mathematical Biology
  • Society for Industrial and Applied Mathematics
  • Association for Women in Mathematics

Publications (selection)

  • with Criminale, WO; TL; Joslin, RD: Theory and computation of hydrodynamic stability. Cambridge Monographs on Mechanics. Cambridge University Press, Cambridge, 2003.
  • A Mathematical Investigation of the Multiple Pathways to Recurrent Prostate Cancer: Comparison with Experimental Data Neoplasia 6 (6) (2004) 697-704.
  • with R. Lai: A Mathematical Model of Receptor-Mediated Apoptosis: Fas Dying to Know Why FasL is a Trimer Mathem. Biosci. Engin. 1 (2) (2004) pp. 325-338.
  • A Mathematical Model of Prostate Tumor Growth and Androgen-Independent Relapse Discrete Contin. Dynam. Sys. 4 (1) (2004) pp. 187-202.
  • with SR Lubkin: Multiphase Mechanics of Capsule Formation in Tumors, J. Biomech. Closely. 124 (2) (2002) pp. 237-243.
  • with HM Byrne: A Mechanical Model of Tumor Encapsulation and Transcapsular Spread Mathem. Biosci. 180 (2002) pp. 307-328.
  • with HM Byrne: A Mathematical Model to Study the Effects of Drug Resistance and Vasculature on the Response of Solid Tumors to Chemotherapy Math. Biosci. 164 (2000) pp. 17-38.
  • with PD Senter, JD Murray: Development and Validation of a Mathematical Model to Describe Anti-cancer Prodrug Activation by Antibody-Enzyme Conjugates, J. Theoret. Med. 2 (2) (2000) pp. 93-111.
  • with SR Lubkin: Theoretical Analysis of Conjugate Localization in Two-Step Cancer Chemotherapy, J. of Math. Bio. (39) 4 (1999) pp. 353-376.

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