William S. Sly
William Shuford Sly (born October 19, 1932 in East St. Louis ) is an American biochemist and molecular biologist .
Sly earned an MD from Saint Louis University in 1957 . Since 1984 he has been Professor of Biochemistry and Molecular Biology there .
Sly and co-workers made important contributions to the elucidation of the biochemical mechanisms by which enzymes reach their respective destination from the endoplasmic reticulum within the cell . Lysosomal enzymes carry mannose-6-phosphate residues, which act as transport signals. Further work deals with the pathogenesis of lysosomal storage diseases .
Mucopolysaccharidosis VII was named Sly syndrome after William S. Sly . Sly's work led to enzyme replacement therapy for Gaucher's disease .
Sly became a member of the National Academy of Sciences in 1989 . In 1991 he and Stuart Kornfeld received the Passano Award .
Web links
- William S. Sly, MD at Saint Louis University (slu.edu); accessed on March 29, 2019
Individual evidence
- ↑ Peter Reuter: Springer Lexicon Medicine. Springer, Berlin a. a. 2004, ISBN 3-540-20412-1 , p. 1989.
- ^ Recipients of the Passano Laureate and Physician Scientist Awards at the Passano Foundation (passanofoundation.org); accessed on March 30, 2019
| personal data | |
|---|---|
| SURNAME | Sly, William S. |
| ALTERNATIVE NAMES | Sly, William Shuford (full name) |
| BRIEF DESCRIPTION | American biochemist and molecular biologist |
| DATE OF BIRTH | October 19, 1932 |
| PLACE OF BIRTH | East St. Louis |