SLC22A18: Difference between revisions
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{{PBB_Summary |
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| summary_text = This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.<ref name="entrez" |
| summary_text = This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.<ref name="entrez" /> |
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*{{cite journal | author=Akiyama S |title=[Mechanisms of drug resistance and reversal of the resistance] |journal=Hum. Cell |volume=14 |issue= 4 |pages= 257–60 |year= 2002 |pmid= 11925925 |doi= }} |
*{{cite journal | author=Akiyama S |title=[Mechanisms of drug resistance and reversal of the resistance] |journal=Hum. Cell |volume=14 |issue= 4 |pages= 257–60 |year= 2002 |pmid= 11925925 |doi= }} |
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*{{cite journal | author=Cooper PR |
*{{cite journal | author=Cooper PR |title=Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain |journal=Genomics |volume=49 |issue= 1 |pages= 38–51 |year= 1998 |pmid= 9570947 |doi= 10.1006/geno.1998.5221 | author2=Smilinich NJ | author3=Day CD | display-authors=3 | last4=Nowak | first4=NJ | last5=Reid | first5=LH | last6=Pearsall | first6=RS | last7=Reece | first7=M | last8=Prawitt | first8=D | last9=Landers | first9=J }} |
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*{{cite journal | author=Reece M |
*{{cite journal | author=Reece M |title=Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules |journal=FEBS Lett. |volume=433 |issue= 3 |pages= 245–50 |year= 1998 |pmid= 9744804 |doi=10.1016/S0014-5793(98)00907-7 | author2=Prawitt D | author3=Landers J | display-authors=3 | last4=Kast | first4=C | last5=Gros | first5=P | last6=Housman | first6=D | last7=Zabel | first7=BU | last8=Pelletier | first8=J }} |
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*{{cite journal | author=Lee MP |
*{{cite journal | author=Lee MP |title=Somatic mutation of TSSC5, a novel imprinted gene from human chromosome 11p15.5 |journal=Cancer Res. |volume=58 |issue= 18 |pages= 4155–9 |year= 1998 |pmid= 9751628 |doi= | author2=Reeves C | author3=Schmitt A | display-authors=3 | last4=Su | first4=K | last5=Connors | first5=TD | last6=Hu | first6=RJ | last7=Brandenburg | first7=S | last8=Lee | first8=MJ | last9=Miller | first9=G }} |
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*{{cite journal | author=Morisaki H, Hatada I, Morisaki T, Mukai T |title=A novel gene, ITM, located between p57KIP2 and IPL, is imprinted in mice |
*{{cite journal | author=Morisaki H, Hatada I, Morisaki T, Mukai T |title=A novel gene, ITM, located between p57KIP2 and IPL, is imprinted in mice |journal=DNA Res. |volume=5 |issue= 4 |pages= 235–40 |year= 1999 |pmid= 9802569 |doi=10.1093/dnares/5.4.235 }} |
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*{{cite journal | author=Onyango P |
*{{cite journal | author=Onyango P |title=Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain |journal=Genome Res. |volume=10 |issue= 11 |pages= 1697–710 |year= 2001 |pmid= 11076855 |doi=10.1101/gr.161800 | author2=Miller W | author3=Lehoczky J | display-authors=3 | last4=Leung | first4=CT | last5=Birren | first5=B | last6=Wheelan | first6=S | last7=Dewar | first7=K | last8=Feinberg | first8=AP }} |
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*{{cite journal | author=Strausberg RL |
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} |
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*{{cite journal | author=Gerhard DS |
*{{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 | author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }} |
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*{{cite journal | author=Yamada HY, Gorbsky GJ |title=Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105 |
*{{cite journal | author=Yamada HY, Gorbsky GJ |title=Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105 |journal=Oncogene |volume=25 |issue= 9 |pages= 1330–9 |year= 2006 |pmid= 16314844 |doi= 10.1038/sj.onc.1209167 | pmc=2713668 }} |
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*{{cite journal | author=Gallagher E |
*{{cite journal | author=Gallagher E |title=Gain of imprinting of SLC22A18 sense and antisense transcripts in human breast cancer |journal=Genomics |volume=88 |issue= 1 |pages= 12–7 |year= 2006 |pmid= 16624517 |doi= 10.1016/j.ygeno.2006.02.004 | author2=Mc Goldrick A | author3=Chung WY | display-authors=3 | last4=Mc Cormack | first4=O. | last5=Harrison | first5=M. | last6=Kerin | first6=M. | last7=Dervan | first7=P.A. | last8=Mc Cann | first8=A. }} |
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Revision as of 06:14, 19 June 2011
Template:PBB Solute carrier family 22 member 18 is a protein that in humans is encoded by the SLC22A18 gene.[1][2][3]
See also
References
- ^ Dao D, Frank D, Qian N, O'Keefe D, Vosatka RJ, Walsh CP, Tycko B (1998). "IMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genes". Hum Mol Genet. 7 (4): 597–608. doi:10.1093/hmg/7.4.597. PMID 9499412.
{{cite journal}}
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ignored (help)CS1 maint: multiple names: authors list (link) - ^ Schwienbacher C, Sabbioni S, Campi M, Veronese A, Bernardi G, Menegatti A, Hatada I, Mukai T, Ohashi H, Barbanti-Brodano G, Croce CM, Negrini M (1998). "Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples". Proc Natl Acad Sci U S A. 95 (7): 3873–8. doi:10.1073/pnas.95.7.3873. PMC 19930. PMID 9520460.
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ignored (help)CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: SLC22A18 solute carrier family 22 (organic cation transporter), member 18".
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.