Sodium/hydrogen exchanger 6
Template:PBB Sodium/hydrogen exchanger 6 is a integral membrane protein that in humans is encoded by the SLC9A6 gene. It was originally thought to be a mitochondrial-targeted protein, but subsequent studies have localized it to the plasma membrane and recycling endosomes[1][2][3][4]
See also
- SLC9A6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
References
- ^ Numata M, Petrecca K, Lake N, Orlowski J (Mar 1998). "Identification of a mitochondrial Na+/H+ exchanger". The Journal of Biological Chemistry. 273 (12): 6951–9. doi:10.1074/jbc.273.12.6951. PMID 9507001.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ "Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria". American Journal of Physiology. Cell Physiology. 282 (5): C1031-41. May 2002. doi:10.1152/ajpcell.00420.2001. PMID 11940519.
{{cite journal}}:|first2=missing|last2=(help);|first3=missing|last3=(help); More than one of author-name-list parameters specified (help) - ^ "Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation". The Journal of Neuroscience. 33 (2): 595–610. Jan 2013. doi:10.1523/JNEUROSCI.2583-12.2013. PMID 23303939.
{{cite journal}}:|first2=missing|last2=(help);|first3=missing|last3=(help); More than one of author-name-list parameters specified (help) - ^ "The Na+/H+ exchanger NHE6 in the endosomal recycling system is involved in the development of apical bile canalicular surface domains in HepG2 cells". Molecular Biology of the Cell. 21 (7): 1293–304. Apr 2010. doi:10.1091/mbc.E09-09-0767. PMC 2847532. PMID 20130086.
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Further reading
- Brett CL, Wei Y, Donowitz M, Rao R (May 2002). "Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria". American Journal of Physiology. Cell Physiology. 282 (5): C1031-41. doi:10.1152/ajpcell.00420.2001. PMID 11940519.
- Cheng J, Moyer BD, Milewski M, Loffing J, Ikeda M, Mickle JE, Cutting GR, Li M, Stanton BA, Guggino WB (Feb 2002). "A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression". The Journal of Biological Chemistry. 277 (5): 3520–9. doi:10.1074/jbc.M110177200. PMID 11707463.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Miyazaki E, Sakaguchi M, Wakabayashi S, Shigekawa M, Mihara K (Dec 2001). "NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell". The Journal of Biological Chemistry. 276 (52): 49221–7. doi:10.1074/jbc.M106267200. PMID 11641397.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Numata M, Orlowski J (May 2001). "Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network". The Journal of Biological Chemistry. 276 (20): 17387–94. doi:10.1074/jbc.M101319200. PMID 11279194.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (Oct 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Research. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
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