Montelukast and Years of Refusal: Difference between pages

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{{futurealbum}}
{{drugbox
{{Infobox Album | <!-- See Wikipedia:WikiProject_Albums -->
| IUPAC_name = 2-[1-<nowiki>[[</nowiki>(1''R'')-1-[3-[2-(7-chloroquinolin-2-yl)ethenyl]<br>phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]<br>sulfanylmethyl]cyclopropyl]acetic acid
|Name = Years of Refusal
| image = Montelukast skeletal.svg
|Type = [[Album]]
| width = 250
|Artist = [[Morrissey]]
| image2 = Montelukast-3D-balls.png
|Cover =
| width2 = 250px
|Released = [[February 2]], [[2009]] (tentative)
| CAS_number = 158966-92-8
|Recorded = Autumn/Winter 2007
| ATC_prefix = R03
|Genre = [[Alternative rock]] |
| ATC_suffix = DC03
|Length =
| PubChem = 60951
|Label = [[Polydor]]/[[Decca Records]]
| DrugBank = APRD00434
|Producer = [[Jerry Finn]]
| C = 35 |H = 36 |Cl = 1 |N = 1 |O = 3 |S = 1
|Last album = ''[[Ringleader of the Tormentors]]''<br/>(2006)
| molecular_weight = 586.184 [[Gram|g]]/[[Mole (unit)|mol]]
|This album = ''Years of Refusal''<br/>(2009)
| smiles = Clc1ccc2ccc(/C=C/c3cccc(c3)C(CCc3ccccc3C(C)(C)O)SCC3(CC3)CC(=O)O)nc2c1
|}}
| bioavailability = 63% to 73%
| protein_bound = 99%
| metabolism = [[Liver|Hepatic]] ([[CYP3A4]] and [[CYP2C9]]-mediated)
| elimination_half-life = 2.7-5.5 hours
| excretion = Biliary
| pregnancy_category = B <small>([[United States|U.S.]])</small>, B1 <small>([[Australia|Au]])</small>
| legal_status = ℞-only <small>(U.S.)</small>, [[Prescription drug|POM]] <small>([[United Kingdom|UK]])</small>, S4 <small>(Au)</small>
| routes_of_administration = Oral
}}
'''Montelukast''' is a [[leukotriene receptor antagonist]] (LTRA) used for the maintenance treatment of [[asthma]] and to relieve symptoms of seasonal [[allergy|allergies]].<ref>Lipkowitz, Myron A. and Navarra, Tova (2001) ''The Encyclopedia of Allergies'' (2nd ed.) Facts on File, New York, p. 178, ISBN 0-8160-4404-X
</ref> It is usually administered orally. Montelukast is a CysLT<sub>1</sub> [[Receptor antagonist|antagonist]]; that is it blocks the action of [[leukotriene]] D4 on the cysteinyl leukotriene receptor CysLT<sub>1</sub> in the lungs and bronchial tubes by binding to it. This reduces the [[bronchoconstriction]] otherwise caused by the leukotriene, and results in less inflammation.


'''''Years of Refusal''''' is the forthcoming ninth solo album by [[Morrissey]], the former lead [[singer]] of [[The Smiths]]. The album, to be distributed by [[Decca Records| Decca]], is set for release on February 2, 2009 in UK and February 3, 2009 in the USA.
Because of its method of operation, it is not useful for the treatment of acute [[asthma attack]]s. Again because of its very specific focus of operation, it does not interact with other allergy medications such as [[theophylline]]. Another leukotriene receptor antagonist is [[zafirlukast]] ([[Accolate]]), taken once daily, and [[zileuton]] ([[Zyflo]]), taken four times per day.


==Side effects==
==Visconti vs Finn==
In an interview on [[BBC Radio 5 Live]] with [[Tony Visconti]], the producer stated that his new project would be "the next Morrissey album", though that this would not be forthcoming for at least a year. However, in an interview with the BBC News website in October 2007, Morrissey said that the album is already written and ready for a possible Autumn 2008 release. In December, Morrissey signed a new deal with [[Decca Records]], which included a ''[[Greatest Hits (Morrissey)|Greatest Hits]]'' album and a newly-recorded album to follow in Autumn 2008. <ref>[http://true-to-you.net/morrissey_news_071203_01 Polydor UK's press release]</ref>


It was announced on [[November 2]], [[2007]] that [[Jerry Finn]], the man behind Morrissey's 2004 album ''[[You Are The Quarry]]'', would be producing the new album instead of Tony Visconti.<ref>[http://www.billboard.com/bbcom/news/article_display.jsp?vnu_content_id=1003667412 Morrissey Eyeing New Album]</ref> A reason for the change was rumored to be related to [[Kristeen Young]], Morrissey's opening act at the time, and Visconti's supposed involvement. Further "proof" of this rumor is the occurrence of L.A. radio station INDIE 103.1's Joe Escalante leaking that Jerry Finn was the producer of the new album the day following Kristeen Young's firing from the 2007/2008 'Greatest Hits' tour. This was also a full week before the official announcement from Decca that Jerry Finn was to produce the new album.
[[Adverse drug reaction|Side effect]]s include [[gastrointestinal tract|gastrointestinal]] disturbances, [[hypersensitivity]] reactions, [[sleep disorder]]s and increased [[bleeding]] tendency, aside from many other generic adverse reactions. Its use is associated with a higher incidence of [[Churg-Strauss_syndrome|Churg-Strauss syndrome]] (whether or not this drug is 'unmasking' subclinical Churg-Strauss is as yet uncertain). In March, 2008 the FDA announced that it would investigate whether mood changes and suicidal thoughts are possible side effects of drugs in this class, including the popular drug Singulair, which currently lists these side effects.<ref>[http://ap.google.com/article/ALeqM5ism9h1KwfQYjFxJVMYhupl8FOU-gD8VLT3QO1 FDA Investigates Suicide With Merck Drug] retrieved on [[06 March]] [[2008]]</ref>


However, in a June 2008 interview with [[Hot Press (magazine)|Hot Press]] magazine Morrissey cleared up the issue:
==Use with loratadine==


{{cquote|Tony wasn't ever in line for the job. He had started working with a band, Kentucky, and tied himself up with that. I wanted to try Jerry Finn again - he had produced ''[[You Are The Quarry]]'', and we were in the enviable situation of having worked both with Tony and Jerry and had really enjoyed both. I'd love to do another album with Tony, and I feel blessed to have eventually found two ideal producers. They are both fantastic in equal measure. I wish I had met them earlier.|}}
[[Schering-Plough]] and [[Merck & Co.|Merck]] have sought permission to market a combined pill with [[loratadine]] (Claritin) and montelukast (Singulair), as many patients combine the two themselves. However, the FDA has found no benefit from a combined pill for seasonal allergies over taking the two drugs in combination<ref>[http://blogs.wsj.com/health/2008/04/28/fda-sneezes-at-claritin-singulair-combo-pill/?mod=WSJBlog Health Blog : FDA Sneezes at Claritin-Singulair Combo Pill<!-- Bot generated title -->]</ref>, and on April 25, 2008, issued a "not approvable" letter for the combination.<ref>[http://www.schering-plough.com/schering_plough/news/release.jsp?releaseID=1135270 Schering-Plough press release - Schering-Plough/MERCK Pharmaceuticals Receives Not-Approvable Letter from FDA for Loratadine/Montelukast]</ref>


On July 18th, a little over a month after the completion of ''Years of Refusal'', producer Jerry Finn suffered a massive brain hemorrhage. After little recovery, Finn was taken off life support August 9th and subsequently passed away on August 21st at the age of 39. <ref>[http://www.reuters.com/article/peopleNews/idUSN2236979720080822 Producer Jerry Finn dies at 39]</ref>
==References==
{{Reflist}}


==Recording and release==
{{Asthma and copd rx}}
Recording for the album commenced in late November and ended in late December in [[Los Angeles]] at Conway Studios. Mixing began in early February 2008. An additional track for the album was recorded in late May according to drummer Matt Walker. <ref>[http://moderndrummer.com/md-blogs-archive/300001321/Matt%20Walker Matt Walker's 'Modern Drummer ' blog]</ref> Album keyboardist [[Roger Joseph Manning Jr.|Roger Manning]] had this to say about the recording of the album:
{{Antihistamines}}
{{Merck&Co}}


{{cquote|I've spent over six weeks recording with Morrissey and his incredible band for what will hopefully become his latest solo effort later this year. Producer Jerry Finn and I have had a long fun filled history together in Punk Pop heaven with groups like Blink 182 and found ourselves both being invited back for our second Morrissey album. I think fans will be pleasantly surprised by this new solo offering. It was all tracked live which added a great punk, garage, DIY urgency to the tracks. I am so used to recording keyboards in the more traditional overdub scenario that being asked to invent parts "on the fly" and track with the band while Morrissey sang live was a very refreshing and challenging experience.|}}<ref>[http://kittyradio.com/soapbox/jukebox/37901-roger-joseph-manning-jr-jellyfish-air-beck-new-album.html Roger Manning speaks on new album]</ref>
[[Category:Leukotriene antagonists]]


On [[May 30]], [[2008]], true-to-you.net posted the following on Morrissey's 2008 album:
[[de:Montelukast]]

[[es:Montelukast]]
{{cquote|Morrissey's new studio album ''Years of Refusal'' is now complete, and is set for a September release by Polydor UK (Universal). It has yet to be decided which Universal label will release the album in the US. ''Years of Refusal'' has 12 tracks and is produced by Jerry Finn.|}} <ref>[http://true-to-you.net/morrissey_news_080530_01 New album information]</ref>
[[no:Montelukast]]

[[pl:Montelukast]]
Of the 12 tracks, current guitarist [[Boz Boorer]] has confirmed he has written 4<ref>[http://www.adam-ant.net/bozb.html Boz Boorer interview]</ref>and former guitarist [[Alain Whyte]] has confirmed he has written 6 or 7<ref>[http://www.indie1031.com/7504_JJ_-_media.php?id=14 Alain Whyte radio interview]</ref>. The other two tracks are [[Jesse Tobias]] compositions.

Originally ''Years of Refusal'' was to be released on September 15, 2008 in the UK and September 16, 2008 in the US. However, the album's release date has since been delayed to February 2, 2009 at the request of Decca UK so Morrissey has time to shop for a new label to distribute the album in the US after he withdrew from Decca US for their 'poor promotion of his ''Greatest Hits'' release'.<ref>[http://true-to-you.net/morrissey_news_080809_01-new-album.html Years of Refusal delayed]</ref>

==Track list==
===Confirmed tracks===
*"[[I'm Throwing My Arms Around Paris]]" (Morrissey/[[Boz Boorer|Boorer]]) †‡¤≠
*"One Day Goodbye Will Be Farewell" (Morrissey/Boorer) †‡¤≠
*"Black Cloud" (Morrissey/Boorer) ¤
*"Mama Lay Softly on the Riverbed" (Morrissey/Whyte) †‡≠
*"Something Is Squeezing My Skull" (Morrissey/Whyte) †‡≠

===Unconfirmed tracks===
The following is the known list of songs recorded post-''[[Ringleader of the Tormentors]]'' that have not been released to this date in any form:

*"Action Man" (Morrissey/[[Alain Whyte|Whyte]]) †
*"Teresa, Teresa" (Morrissey/Whyte) †
*"When I Was Young" (Morrissey/Whyte) †
*"When Last I Spoke to Carol" (Morrissey/Whyte) †
*"You Were Good in Your Time" (Morrissey/Whyte) †
*"Because of My Poor Education" (Morrissey/Whyte) †
*"I Was Bully, Do Not Forget Me" (Morrissey/Whyte) †
*"It's Not Your Birthday Anymore" (Morrissey/Whyte) †
*"I'm Looking Forward to Going Back" (Morrissey/Whyte) †
*"Livings" (Morrissey/Whyte)
*"The Longer I Live" (Morrissey/[[Jesse Tobias| Tobias]]) ≈

===Other tracks===
The following are previously released tracks that are said to appear on the album or as B-sides to it's subsequent singles:

*"[[My Dearest Love]]" (Morrissey/Whyte) †
*"[[That's How People Grow Up]]" (Morrissey/Boorer) †‡¤
*"[[All You Need Is Me]]" (Morrissey/Tobias) †‡
*"[[Children In Pieces]]" (Morrissey/Tobias)
*"You Say You Don't Love Me" ([[Pete Shelley|Shelley]])

: † <small>Listed on Warner-Chappell</small>
: ‡ <small>Played live on the 2007/2008 'Greatest Hits' tour.</small>
: ≈ <small>Confirmed by drummer Matt Walker.</small>
: ¤ <small>Confirmed by Boz Boorer during a recent interview. (http://www.adam-ant.net/bozb.html)
: ≠ <small>Confirmed by Morrissey during concerts and interviews.
</small>

== Singles ==
According to [[Boz Boorer]], "[[I'm Throwing My Arms Around Paris]]" will be the first single off the album. <ref>http://www.morrissey-solo.com/article.pl?sid=08/07/27/1715246</ref>

== Musicians ==
=== The Band ===
* [[Morrissey]] - Vocals
* [[Boz Boorer]] - Guitars
* [[Jesse Tobias]] - Guitars
* Solomon Walker - Bass guitar
* Matt Walker - Drums
* [[Roger Joseph Manning Jr.|Roger Manning]] - Keyboards

==Trivia==
{{trivia|date=July 2008}}

* Though he wrote half the songs on the album, former Morrissey guitarist Alain Whyte did not participate in the recording of the album.
* While on tour, Morrissey joked that the song "[[I'm Throwing My Arms Around Paris]]" was originally written as his entry to the 2007 [[Eurovision]] song contest.
* "Something Is Squeezing My Skull", "Mama Lay Softly on the Riverbed", "[[I'm Throwing My Arms Around Paris]]" and "One Day Goodbye Will Be Farewell", were all debuted on Morrissey's 2007/2008 'Greatest Hits Tour'.
* Keyboardist Michael Farrell left the band prior to the album's completion. Morrissey recruited [[Roger Joseph Manning Jr.|Roger Manning]] to fill in. Manning previously played on Morrissey's 2004 album ''[[You Are The Quarry]]''.
* Despite the onstage incident in which [[Kristeen Young]] was dismissed from Morrissey's 2007/2008 'Greatest Hits Tour', she was invited to join him at the 2008 [[O2 Wireless Festival]] at Hyde Park in July. Morrissey has also asked Young to once again join him for the upcoming 'Years of Refusal Tour'.

== References ==
{{reflist}}

{{Morrissey}}

[[Category:2009 albums]]
[[Category:Morrissey albums]]
[[Category:Albums produced by Jerry Finn]]

[[sv:Years of Refusal]]

Revision as of 10:36, 10 October 2008

Template:Futurealbum

Untitled

Years of Refusal is the forthcoming ninth solo album by Morrissey, the former lead singer of The Smiths. The album, to be distributed by Decca, is set for release on February 2, 2009 in UK and February 3, 2009 in the USA.

Visconti vs Finn

In an interview on BBC Radio 5 Live with Tony Visconti, the producer stated that his new project would be "the next Morrissey album", though that this would not be forthcoming for at least a year. However, in an interview with the BBC News website in October 2007, Morrissey said that the album is already written and ready for a possible Autumn 2008 release. In December, Morrissey signed a new deal with Decca Records, which included a Greatest Hits album and a newly-recorded album to follow in Autumn 2008. [1]

It was announced on November 2, 2007 that Jerry Finn, the man behind Morrissey's 2004 album You Are The Quarry, would be producing the new album instead of Tony Visconti.[2] A reason for the change was rumored to be related to Kristeen Young, Morrissey's opening act at the time, and Visconti's supposed involvement. Further "proof" of this rumor is the occurrence of L.A. radio station INDIE 103.1's Joe Escalante leaking that Jerry Finn was the producer of the new album the day following Kristeen Young's firing from the 2007/2008 'Greatest Hits' tour. This was also a full week before the official announcement from Decca that Jerry Finn was to produce the new album.

However, in a June 2008 interview with Hot Press magazine Morrissey cleared up the issue:

Tony wasn't ever in line for the job. He had started working with a band, Kentucky, and tied himself up with that. I wanted to try Jerry Finn again - he had produced You Are The Quarry, and we were in the enviable situation of having worked both with Tony and Jerry and had really enjoyed both. I'd love to do another album with Tony, and I feel blessed to have eventually found two ideal producers. They are both fantastic in equal measure. I wish I had met them earlier.

On July 18th, a little over a month after the completion of Years of Refusal, producer Jerry Finn suffered a massive brain hemorrhage. After little recovery, Finn was taken off life support August 9th and subsequently passed away on August 21st at the age of 39. [3]

Recording and release

Recording for the album commenced in late November and ended in late December in Los Angeles at Conway Studios. Mixing began in early February 2008. An additional track for the album was recorded in late May according to drummer Matt Walker. [4] Album keyboardist Roger Manning had this to say about the recording of the album:

I've spent over six weeks recording with Morrissey and his incredible band for what will hopefully become his latest solo effort later this year. Producer Jerry Finn and I have had a long fun filled history together in Punk Pop heaven with groups like Blink 182 and found ourselves both being invited back for our second Morrissey album. I think fans will be pleasantly surprised by this new solo offering. It was all tracked live which added a great punk, garage, DIY urgency to the tracks. I am so used to recording keyboards in the more traditional overdub scenario that being asked to invent parts "on the fly" and track with the band while Morrissey sang live was a very refreshing and challenging experience.

[5]

On May 30, 2008, true-to-you.net posted the following on Morrissey's 2008 album:

Morrissey's new studio album Years of Refusal is now complete, and is set for a September release by Polydor UK (Universal). It has yet to be decided which Universal label will release the album in the US. Years of Refusal has 12 tracks and is produced by Jerry Finn.

[6]

Of the 12 tracks, current guitarist Boz Boorer has confirmed he has written 4[7]and former guitarist Alain Whyte has confirmed he has written 6 or 7[8]. The other two tracks are Jesse Tobias compositions.

Originally Years of Refusal was to be released on September 15, 2008 in the UK and September 16, 2008 in the US. However, the album's release date has since been delayed to February 2, 2009 at the request of Decca UK so Morrissey has time to shop for a new label to distribute the album in the US after he withdrew from Decca US for their 'poor promotion of his Greatest Hits release'.[9]

Track list

Confirmed tracks

  • "I'm Throwing My Arms Around Paris" (Morrissey/Boorer) †‡¤≠
  • "One Day Goodbye Will Be Farewell" (Morrissey/Boorer) †‡¤≠
  • "Black Cloud" (Morrissey/Boorer) ¤
  • "Mama Lay Softly on the Riverbed" (Morrissey/Whyte) †‡≠
  • "Something Is Squeezing My Skull" (Morrissey/Whyte) †‡≠

Unconfirmed tracks

The following is the known list of songs recorded post-Ringleader of the Tormentors that have not been released to this date in any form:

  • "Action Man" (Morrissey/Whyte) †
  • "Teresa, Teresa" (Morrissey/Whyte) †
  • "When I Was Young" (Morrissey/Whyte) †
  • "When Last I Spoke to Carol" (Morrissey/Whyte) †
  • "You Were Good in Your Time" (Morrissey/Whyte) †
  • "Because of My Poor Education" (Morrissey/Whyte) †
  • "I Was Bully, Do Not Forget Me" (Morrissey/Whyte) †
  • "It's Not Your Birthday Anymore" (Morrissey/Whyte) †
  • "I'm Looking Forward to Going Back" (Morrissey/Whyte) †
  • "Livings" (Morrissey/Whyte)
  • "The Longer I Live" (Morrissey/ Tobias) ≈

Other tracks

The following are previously released tracks that are said to appear on the album or as B-sides to it's subsequent singles:

† Listed on Warner-Chappell
‡ Played live on the 2007/2008 'Greatest Hits' tour.
≈ Confirmed by drummer Matt Walker.
¤ Confirmed by Boz Boorer during a recent interview. (http://www.adam-ant.net/bozb.html)
≠ Confirmed by Morrissey during concerts and interviews.

Singles

According to Boz Boorer, "I'm Throwing My Arms Around Paris" will be the first single off the album. [10]

Musicians

The Band

Trivia

  • Though he wrote half the songs on the album, former Morrissey guitarist Alain Whyte did not participate in the recording of the album.
  • While on tour, Morrissey joked that the song "I'm Throwing My Arms Around Paris" was originally written as his entry to the 2007 Eurovision song contest.
  • "Something Is Squeezing My Skull", "Mama Lay Softly on the Riverbed", "I'm Throwing My Arms Around Paris" and "One Day Goodbye Will Be Farewell", were all debuted on Morrissey's 2007/2008 'Greatest Hits Tour'.
  • Keyboardist Michael Farrell left the band prior to the album's completion. Morrissey recruited Roger Manning to fill in. Manning previously played on Morrissey's 2004 album You Are The Quarry.
  • Despite the onstage incident in which Kristeen Young was dismissed from Morrissey's 2007/2008 'Greatest Hits Tour', she was invited to join him at the 2008 O2 Wireless Festival at Hyde Park in July. Morrissey has also asked Young to once again join him for the upcoming 'Years of Refusal Tour'.

References

  1. ^ Polydor UK's press release
  2. ^ Morrissey Eyeing New Album
  3. ^ Producer Jerry Finn dies at 39
  4. ^ Matt Walker's 'Modern Drummer ' blog
  5. ^ Roger Manning speaks on new album
  6. ^ New album information
  7. ^ Boz Boorer interview
  8. ^ Alain Whyte radio interview
  9. ^ Years of Refusal delayed
  10. ^ http://www.morrissey-solo.com/article.pl?sid=08/07/27/1715246
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