2,4-diaminopyrimidine

Structural formula
General
Surname	2,4-diaminopyrimidine
other names	2,4-DAP Pyrimidine-2,4-diylenediamine
Molecular formula	C 4 H 6 N 4
Brief description	light yellow solid
External identifiers / databases
CAS number 156-81-0 EC number 205-862-3 ECHA InfoCard 100.005.331 PubChem 67431 Wikidata Q209196
properties
Molar mass	110.12 g mol −1
Physical state	firmly
Melting point	143-147 ° C
solubility	light in water (840 g l −1 at 25 ° C)
Refractive index	1.46
safety instructions
GHS labeling of hazardous substances Caution H and P phrases H: 315-319-335 P: 261-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

2,4-Diaminopyrimidine is a heterocyclic organic compound and belongs to the group of the diaminopyrimidines . It is a folic acid antagonist, so it blocks the synthesis of folic acid in bacteria. Folic acid is an important growth substance for many bacteria.

It is used together with xanthine to investigate unusual base pairings in DNA .

Web links

• Freepatentsonline: 2,4-Diaminopyrimidines

Individual evidence

1. ↑ ^{a b c d} data sheet 2,4-diaminopyrimidine from Sigma-Aldrich , accessed on November 13, 2017 ( PDF ).
2. ↑ ^{a b} Entry on 2,4-diaminopyrimidines at ChemBlink , accessed on November 13, 2017.
3. ^ ST Madariaga, JG Contreras: Tautomerism of xanthine and its pairing with 2,6-diaminopyrimidine: An ab initio study in the gas phase and aqueous solution . In: J. Chil. Chem. Soc. , 2003 , 48  (4), pp. 129-133. doi : 10.4067 / S0717-97072003000400021 .