3,4-dimethoxyphenethylamine

Structural formula
General
Surname	3,4-dimethoxyphenethylamine
other names	Homoveratrylamine; 2- (3,4-dimethoxyphenyl) ethylamine; DMPEA;
Molecular formula	C 10 H 15 NO 2
Brief description	yellowish liquid with an amine-like odor
External identifiers / databases
EC number	204-376-9
ECHA InfoCard	100.003.979
PubChem	8421
ChemSpider	8114
Wikidata	Q4634069
properties
Molar mass	181.24 g mol −1
Physical state	liquid
density	1.09 g cm −3
Melting point	12 ° C
boiling point	188 ° C (20 hPa)
solubility	miscible with water
Refractive index	1.5464 (20 ° C)
safety instructions
H and P phrases	H: 302-315-318
	P: 261-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

3,4-Dimethoxyphenethylamine is a chemical compound from the group of catecholamines and phenylethylamines .

Occurrence

3,4-Dimethoxyphenethylamine occurs naturally in Desmodium tiliaefolium , Pachycereus pecten-aboriginum , Trichocereus peruvianus and other Trichocereus species, Echinocereus merkeri and Lophophora williamsii (peyote).

Extraction and presentation

3,4-Dimethoxyphenethylamine can be obtained from 3,4-dimethoxyphenethylamide .

properties

3,4-Dimethoxyphenethylamine is a flammable, hardly inflammable, light and air sensitive, yellowish liquid with an amine-like odor, which is miscible with water.

use

3,4-Dimethoxyphenethylamine is used as a precursor for the synthesis of isoquinolines (verapamil).

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on 3,4-dimethoxyphenethylamine in the GESTIS substance database of the IFA , accessed on March 27, 2019(JavaScript required) .
↑ David R. Lide: CRC Handbook of Chemistry and Physics A Ready-reference Book of Chemical and Physical Data . CRC Press, 1995, ISBN 978-0-8493-0595-5 , pp. 206 ( limited preview in Google Book search).
↑ ^a ^b Data sheet 3,4-Dimethoxyphenethylamine, 97% from Sigma-Aldrich , accessed on March 27, 2019 ( PDF ).
^ Ian W. Southon, John Buckingham: Dictionary of Alkaloids, Second Edition with CD-ROM . CRC Press, 1989, ISBN 978-0-412-24910-5 , pp. 362 ( limited preview in Google Book search).
^ Karl Hugo Bauer: The current state of the synthesis of plant alkaloids . Springer-Verlag, 2013, ISBN 978-3-322-98841-6 , pp. 76 ( limited preview in Google Book search).

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on 3,4-dimethoxyphenethylamine in the GESTIS substance database of the IFA , accessed on March 27, 2019(JavaScript required) .

[David_R._Lide-2] David R. Lide: CRC Handbook of Chemistry and Physics A Ready-reference Book of Chemical and Physical Data . CRC Press, 1995, ISBN 978-0-8493-0595-5 , pp. 206 ( limited preview in Google Book search).

[Sigma-3] Data sheet 3,4-Dimethoxyphenethylamine, 97% from Sigma-Aldrich , accessed on March 27, 2019 ( PDF ).

[Ian_W._Southon,_John_Buckingham-4] Ian W. Southon, John Buckingham: Dictionary of Alkaloids, Second Edition with CD-ROM . CRC Press, 1989, ISBN 978-0-412-24910-5 , pp. 362 ( limited preview in Google Book search).

[Karl_Hugo_Bauer-5] Karl Hugo Bauer: The current state of the synthesis of plant alkaloids . Springer-Verlag, 2013, ISBN 978-3-322-98841-6 , pp. 76 ( limited preview in Google Book search).