ADDA (amino acid)

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Structural formula
Structural formula of ADDA
General
Surname ADDA (amino acid)
other names
  • (2 S , 3 S , 4 E , 6 E , 8 S , 9 S ) -3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid
  • ADDA
Molecular formula C 20 H 29 NO 3
External identifiers / databases
CAS number 126456-06-2
PubChem 57357424
ChemSpider 20137047
Wikidata Q9137074
properties
Molar mass 331.46 g mol −1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

ADDA or 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid is a non-proteinogenic amino acid found in toxins ( microcystins ) produced by cyanobacteria , such as microcystin LR and Nodularin .

The toxic effect of the microcystins is based on an inhibition of the serine / threonine-specific protein phosphatases PP1, PP2a and PP3, which is very likely due to ADDA.

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ a b Entry on algae toxins. In: Römpp Online . Georg Thieme Verlag, accessed on May 4, 2016.