AH-7921

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Structural formula
Structural formula of AM-2201
General
Surname AH-7921
other names

3,4-dichloro- N - [(1-dimethylamino) cyclohexylmethyl] benzamide

Molecular formula C 16 H 22 Cl 2 N 2 O
External identifiers / databases
CAS number 55154-30-8
PubChem 187760
Wikidata Q4651730
properties
Molar mass 329.27 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

AH-7921 is a synthetically produced chemical compound from the group of opioids .

history

AH-7921 was first synthesized in the 1970s by a team from Allan and Hanburys (now GlaxoSmithKline ).

pharmacology

AH-7921 acts mainly on the µ-receptors . The analgesic potency , which always applies in comparison to morphine , is around 0.8 after oral administration.

use

AH-7921 is not used in medicine. It is sold by a few Research Chemicals shops and is sometimes added in low doses to smoking mixtures , which also contain cannabinoid mimetics and are intended for abuse as intoxicants .

Legal position

  • European Union
On September 25, 2014, the EU banned AH-7921, among other things. The manufacture and sale of the substance has therefore been prohibited since then. The EU states then had one year to implement the ban.

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Entry on 3,4-Dichloro-N - {[1- (dimethylamino) cyclohexyl] methyl} benzamide Template: link text check / apostrophe in the ChemSpider database of the Royal Society of Chemistry , accessed on July 23, 2013.
  3. ^ RT Brittain, DN Kellett, ML Neat, R. Stables: Proceedings: Anti-nociceptive effects in N-substituted cyclohexylmethylbenzamides . In: British Journal of Pharmacology . 49, No. 1, 1973, pp. 158P-159P. PMID 4207044 . PMC 1776456 (free full text).
  4. ↑ N. Uchiyama, S. Matsuda, M. Kawamura, R. Kikura-Hanajiri, Y. Goda: Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products . In: Forensic Toxicology . 2013. doi : 10.1007 / s11419-013-0182-9 .
  5. ↑ Implementing decision of the Council of September 25, 2014 (2014/688 / EU) (PDF) accessed on October 17, 2014
  6. ↑ Aerzteblatt.de: EU bans four dangerous designer drugs, September 26, 2014, accessed on October 17, 2014
  7. ↑ Rp-online.de: MDPV, 25I-NBOMe, AH-7921 and Methoxetamine EU bans four novel drugs, September 25, 2014 accessed on October 17, 2014