Acid Red 94

Structural formula
	Structure of CI Acid Red 94 as a lactone in the phenolic form
General
Surname	CI Acid Red 94
other names	4,5,6,7-tetrachloro-3 ′, 6′-dihydroxy-2 ′, 4 ′, 5 ′, 7′-tetraiodspiro [isobenzofuran-1 (3 H ), 9 ′ - [9 H ] xanthene] - 3-on; Rose Bengal Lactone; 4,5,6,7-tetrachloro-2 ', 4', 5 ', 7'-tetraiodofluorescein; CI 45440;
Molecular formula	C 20 H 4 Cl 4 I 4 O 5 (phenol form, lactone )
External identifiers / databases
EC number	223-993-4
ECHA InfoCard	100,021,813
PubChem	69439
Wikidata	Q11350933
properties
Molar mass	973.67 g mol −1 (phenol form, lactone )
Physical state	firmly
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: no H-phrases
	P: no P-phrases
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

CI Acid Red 94 is a chemical compound from the group of triphenylmethane dyes and xanthene dyes .

Microscope image showing the use of rose bengal as a dye.

The dye is used, among other things, in the rose bengal test, in which the administered compound is eliminated unchanged by the liver and excreted in the bile. The excretory capacity of the liver can then be quantified on the basis of the elimination rate.

Acid Red 94 can also be used to test for the presence of Brucellae .

structure

Depending on the pH value , the dye is available in the uncharged spiro- lactone form or as a mono-, di- or trisodium salt. The disodium salt of the compound can be formulated as a lactone or as a carboxylate .

CI Acid Red 94, Di-Na-Salt
CAS 632-69-9

CI Acid Red 94, Di-Na-Salt
CAS 11121-48-5

Individual evidence

↑ ^a ^b Data sheet Rose Bengal lactone from Sigma-Aldrich , accessed on October 14, 2019 ( PDF ).
↑ Axel M. Gressner, Torsten Arndt (Ed.): Lexicon of the Medical Laboratory Diagnostics . 2nd, revised and expanded edition. Springer, Berlin, Heidelberg 2013, ISBN 978-3-642-12921-6 , entry on rose bengal test , doi : 10.1007 / 978-3-642-12921-6 .
↑ Rose Bengal plate test (RBT) for Brucella: Principle, Procedure and limitation
↑ External identifiers or database links for CI Acid Red 94, Di-Na-Salz, Lacton: CAS number: 632-69-9, EC number: 211-183-3, ECHA InfoCard: 100.010.168 , PubChem : 69438 , Wikidata : Q71002708 .
↑ External identifiers or database links for CI Acid Red 94, Di-Na-Salt, Carboxylate : CAS number: 11121-48-5, EC number: 601-063-2, ECHA InfoCard: 100.115.989 , PubChem : 32343 , Wikidata : Q71003731 .

[Sigma-1] Data sheet Rose Bengal lactone from Sigma-Aldrich , accessed on October 14, 2019 ( PDF ).

[2] Axel M. Gressner, Torsten Arndt (Ed.): Lexicon of the Medical Laboratory Diagnostics . 2nd, revised and expanded edition. Springer, Berlin, Heidelberg 2013, ISBN 978-3-642-12921-6 , entry on rose bengal test , doi : 10.1007 / 978-3-642-12921-6 .

[3] Rose Bengal plate test (RBT) for Brucella: Principle, Procedure and limitation

[4] External identifiers or database links for CI Acid Red 94, Di-Na-Salz, Lacton: CAS number: 632-69-9, EC number: 211-183-3, ECHA InfoCard: 100.010.168 , PubChem : 69438 , Wikidata : Q71002708 .

[5] External identifiers or database links for CI Acid Red 94, Di-Na-Salt, Carboxylate : CAS number: 11121-48-5, EC number: 601-063-2, ECHA InfoCard: 100.115.989 , PubChem : 32343 , Wikidata : Q71003731 .