Bruce AD ​​Stocker

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Bruce Arnold Dunbar Stocker (born May 26, 1917 in England ; † August 30, 2004 in Palo Alto ), he published under BAD Stocker and later Bruce AD ​​Stocker, was an American microbiologist and immunologist, professor at Stanford University .

Stocker was a native of Britain and studied medicine at King's College, University of London and Westminster Hospital Medical School, specializing in pathology and graduating in 1940. During World War II he served as a doctor in the Royal Air Force in India and Burma. After returning to Great Britain in 1947, he went to the London School of Hygiene and Tropical Medicine in London, where he began his lifelong studies on salmonella , which he first published in 1949. In 1951 he was with Joshua Lederberg and Norton Zinder in Madison (Wisconsin). In 1953 Stocker, Lederberg and Zinder published a paper in which they demonstrated the transfer of linked genes between bacteria by bacteriophages. In the same year he became head of the Guinness-Lister Microbiological Research Unit at the Lister Institute in London. In 1966 he became a professor at Stanford University, where he headed the Faculty of Medical Microbiology from 1976 to 1981. In 1987 he officially retired, but continued research and published until his death - some of his work even appeared posthumously.

Stocker did research in particular on salmonella, against which he also developed vaccines. His starting point were genetically modified strains that needed certain aromatic amino acids for their growth and could not multiply in mammalian hosts, but stimulated the immune system against Salmonella. He wanted to use such genetically modified Salmonella strains as vectors that should stimulate antibody production against other bacteria and tumors.

In 1965 he received the Paul Ehrlich and Ludwig Darmstaedter Prize . In 1966 he became a Fellow of the Royal Society .

He was married and had two daughters.

Web links

Individual evidence

  1. Page on Stocker's work on Vaccines Based on Genetically Modified Salmonella at Stanford University , accessed March 4, 2012