Cannabielsoin

Structural formula
General
Surname	Cannabielsoin
other names	CBE; (5a S , 6 S , 9 R , 9a R ) -6-Methyl-3-pentyl-9-prop-1-en-2-yl-7,8,9,9a-tetrahydro-5a H -dibenzofuran-1 , 6-diol ( IUPAC ) ; (1 R , 9 S , 10 S , 13 R ) -10-methyl-5-pentyl-13- (prop-1-en-2-yl) -8-oxatricyclo [7.4.0.0 2.7 ] trideca-2 (7), 3,5-triene-3,10-diol;
Molecular formula	C 21 H 30 O 3
External identifiers / databases
PubChem	162113
ChemSpider	142372
Wikidata	Q22668702
Drug information
Drug class	Cannabinoids
properties
Molar mass	330.46 g mol −1
safety instructions
GHS hazard labeling ; no classification available
GHS hazard labeling ; no classification available
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cannabielsoin ( CBE ) is a cannabinoid first observed in 1983 by researchers at Ohio State University while studying the metabolism of cannabidiol , the metabolite of which it is. Cannabielsoin was then studied for its biological formation at the University of Hokuriku in Japan .

In suspension cultures of Cannabis sativa and Saccharum officinarum , cannabielsoin is present under normal growth conditions. It could also be detected in the liver of guinea pigs to which cannabidiol had been administered intraperitoneally an hour earlier . The compound shows little effect on body temperature and pentobarbital-induced sleep.

A total of five different cannabinoids in this group are known to date.

Individual evidence

↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
^ ^A ^b I. Yamamoto, H. Gohda, S. Narimatsu, H. Yoshimura: Identification of cannabielsoin, a new metabolite of cannabidiol formed by guinea-pig hepatic microsomal enzymes, and its pharmacological activity in mice. In: J Pharmacobiodyn. December 1988, PMID 3254981 .
↑ Roger Pertwee: Handbook of Cannabis . OUP Oxford, 2014, ISBN 978-0-19-163969-2 , pp. 11 ( limited preview in Google Book search).

[NV-1] This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

[CBE-2] A ^b I. Yamamoto, H. Gohda, S. Narimatsu, H. Yoshimura: Identification of cannabielsoin, a new metabolite of cannabidiol formed by guinea-pig hepatic microsomal enzymes, and its pharmacological activity in mice. In: J Pharmacobiodyn. December 1988, PMID 3254981 .

[Roger_Pertwee-3] Roger Pertwee: Handbook of Cannabis . OUP Oxford, 2014, ISBN 978-0-19-163969-2 , pp. 11 ( limited preview in Google Book search).