Cereulid

Structural formula
General
Surname	Cereulid
other names	( D -Ala- D - O -Leu-L-Val) 3
Molecular formula	C 57 H 96 N 6 O 18
External identifiers / databases
CAS number 157232-64-9 PubChem 10057089 ChemSpider 8232646 Wikidata Q14949467
properties
Molar mass	1152 g mol −1
Physical state	firmly
safety instructions
GHS hazard labeling no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cereulide is an emetic toxin produced by the virulent Bacillus cereus . It is formed in the bacterial cell via a non-ribosomal peptide synthethase.

proof

The detection can be done in a bioassay with boar spermatozoa . In addition, there is a method using liquid chromatography with mass spectrometry coupling according to DIN EN ISO 18465.

Individual evidence

1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
2. ↑ Sandra Marxen, Timo D. Stark, Elrike Frenzel, Andrea Rütschle, Genia Lücking: Chemodiversity of cereulide, the emetic toxin of Bacillus cereus . In: Analytical and Bioanalytical Chemistry . tape 407 , no. 9 , March 1, 2015, p. 2439-2453 , doi : 10.1007 / s00216-015-8511-y .
3. ↑ Diego A. Alonzo, Nathan A. Magarvey, T. Martin Schmeing: Characterization of Cereulide Synthetase, a Toxin-Producing Macromolecular Machine . In: PLOS ONE . tape 10 , no. 6 , June 4, 2015, p. e0128569 , doi : 10.1371 / journal.pone.0128569 .
4. ↑ MA Andersson, R. Mikkola, J. Helin, MC Andersson, M. Salkinoja-Salonen: A novel sensitive bioassay for detection of Bacillus cereus emetic toxin and related depsipeptide ionophores . In: Applied and Environmental Microbiology . tape 64 , no. 4 , April 1998, pp. 1338-1343 , PMID 9546170 .
5. ↑ Burkhard Schütze, LADR food analysis : Bacillus cereus in food - a differentiated risk assessment is possible nowadays! ( Full text at Researchgate ), Deutsche Lebensmittel-Rundschau , May 2017