Chinese tree snare
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Chinese tree snare ( Periploca sepium ) |
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| Periploca sepium | ||||||||||||
| Bunge |
The Chinese tree snare ( Periploca sepium , Chinese 杠 柳 , Pinyin gàng liǔ ) is a species of plant from the dog poison family (Apocynaceae).
features
The Chinese tree loop is a deciduous shrub with a height of up to 4 meters. The leaves are oblong-oval with a triangular base and a pointed tip with a length of 5 to 9 centimeters and a width of 1.5 to 2.5 centimeters. They have 20 to 25 cross veins. The petiole is about 0.5 inches long.
The zymous , often paired inflorescences have few flowers and are on short side branches. The flowers are on a stalk about 2 centimeters long. The sepals are rounded, triangular and 2 to 3 millimeters long. The corolla is purple with a diameter of about 1.5 centimeters. The individual petals are fused to form a tube about 3 millimeters long, the free tips are about 8 millimeters long, elongated, ovoid and shiny. Their outside is hairless, on the inside they have hair especially towards the middle, in the center there is a bald spot. The secondary crown is bare. The flowering period is from May to June.
The follicles are cylindrical, 7 to 12 centimeters long and often connected in pairs at the tip. Fruits are borne from June to July.
The chromosome set is 2n = 22.
Occurrence
The Chinese tree snare occurs on the Chinese mainland with the exception of the provinces of Guangdong , Guangxi , Hainan and also in Far Eastern Asian Russia. The habitat are plains, slopes and forest edges.
use
The Chinese tree loop is used in traditional Chinese medicine to treat rheumatoid arthritis . In laboratory tests, an inhibiting effect of the plant extract on the growth and interleukin -6 release of fibroblasts from rheumatic tissue could be demonstrated. In addition, a study on mice with the substance periplocoside A isolated from the Chinese tree snare suggests a protective effect on liver tissue in the case of autoimmune hepatitis. In the study, T-cell-mediated hepatites were triggered by Concanavalin A in mice . Pretreatment with periplocoside A significantly reduced liver damage. The prevention of liver cell necrosis is likely related to the significant reduction in the levels of interleukin (IL) -4, interferon (IFN) -gamma and serum alanin transaminase (ALT) levels by periplocoside A. In vitro studies have shown that periplocoside A suppresses the release of inflammatory cytokines such as IL-4 and IL-17 as well as (IFN) -gamma. In addition, no apparent toxicity was observed.
swell
Individual evidence
- ^ Periploca sepium at Tropicos.org. In: IPCN Chromosome Reports . Missouri Botanical Garden, St. Louis
- ↑ Rafaël Govaerts (Ed.): Periploca - World Checklist of Selected Plant Families of the Royal Botanic Gardens, Kew. Last accessed on November 12, 2017.
- ↑ Tokiwa Takayoshi; Harada Kuniaki; Matsumura Toshiharu; Tukiyama Takashi: Oriental medicinal herb, Periploca sepium, extract inhibits growth and IL-6 production of human synovial fibroblast-like cells . In: Biological and Pharmaceutical Bulletin . No. 27 (10), 2004, pp. 1691-1693.
- ↑ Wan J., Zhu YN, Feng JQ, Chen HJ, Zhang RJ, Ni J., Chen ZH, Hou LF, Liu QF, Zhang J., et al .: Periplocoside a, a pregnane glycoside from periploca sepium bge, prevents concanavalin a-induced mice hepatitis through inhibiting nkt-derived inflammatory cytokine productions. . In: Int. Immunopharmacol. . No. 2008; 8, August, pp. 1248-1256 .. PMID 18602071 .
- ^ Yao N., Wang X .: In vitro immunomodulatory activity of oxymatrine on toll-like receptor 9 signal pathway in chronic hepatitis . In: Am. J. Chin. Med. . August. PMID 19597527 .
