Dihydrofolic acid

Structural formula
General
Surname	Dihydrofolic acid
other names	7,8-dihydropteroyl-L-glutamic acid; Dihydropteroyl-L-glutamic acid; FAH 2 ;
Molecular formula	C 19 H 21 N 7 O 6
External identifiers / databases
EC number	609-824-0
ECHA InfoCard	100.116.435
PubChem	98792
ChemSpider	89228
DrugBank	DB02015
Wikidata	Q192367
properties
Molar mass	443.41 g mol −1
Physical state	firmly
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 315-319-335
	P: 261-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Dihydrofolic acid is an intermediate in the synthesis of tetrahydrofolic acid from folic acid by dihydrofolate reductase . Their salts are called dihydrofolates.

Some drugs such as sulfonamides inhibit the synthesis of dihydrofolic acid.

Individual evidence

↑ ^a ^b ^c Data sheet Dihydrofolic acid, ≥90% from Sigma-Aldrich , accessed on March 11, 2013 ( PDF ).
↑ Heinz Lüllmann, Klaus Mohr, Lutz Hein: Pharmacology and Toxicology: Understanding the Effects of Medicines - Medicines ... Georg Thieme Verlag, 2010, ISBN 3-13-151647-X , p. 490 ( limited preview in Google Book search).

↑ Hermann Plötz: Small drug apprenticeship for specialist occupations in health care . Springer DE, 2012, ISBN 3-642-29986-5 , p. 184 ( limited preview in Google Book search).

[Sigma-1] Data sheet Dihydrofolic acid, ≥90% from Sigma-Aldrich , accessed on March 11, 2013 ( PDF ).

[Heinz_Lüllmann,_Klaus_Mohr,_Lutz_Hein-2] Heinz Lüllmann, Klaus Mohr, Lutz Hein: Pharmacology and Toxicology: Understanding the Effects of Medicines - Medicines ... Georg Thieme Verlag, 2010, ISBN 3-13-151647-X , p. 490 ( limited preview in Google Book search).

[Hermann_Plötz-3] Hermann Plötz: Small drug apprenticeship for specialist occupations in health care . Springer DE, 2012, ISBN 3-642-29986-5 , p. 184 ( limited preview in Google Book search).