Dithioerythritol
Structural formula | |||||||||||||||||||
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General | |||||||||||||||||||
Surname | Dithioerythritol | ||||||||||||||||||
other names |
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Molecular formula | C 4 H 10 O 2 S 2 | ||||||||||||||||||
Brief description |
white solid with an unpleasant odor |
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properties | |||||||||||||||||||
Molar mass | 154.25 g mol −1 | ||||||||||||||||||
Physical state |
firmly |
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Melting point |
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solubility |
good in water (1500 g l −1 , 20 ° C, DL - threo form) |
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safety instructions | |||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
1,4-Dithioerythritol or dithioerythritol (DTE) is a chemical compound that is derived from the sugar alcohol erythritol by replacing the oxygen atoms in the terminal hydroxyl groups with sulfur atoms. Dithioerythritol is the diastereomer of dithiothreitol (DTT) and, like erythritol, is stereochemically a meso compound . DTE is a good reducing agent and, like DTT, cleaves disulfide bridges in proteins , which is why it is used in the sample buffer in SDS-PAGE, among other things .
See also
Individual evidence
- ↑ a b c d e f g Entry on 1,4-Dimercapto-2,3-butanediol in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .