Polysorbate 60

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Structural formula
Structure of polysorbate 60, (w + x + y + z = 20)
Typical structure of polysorbate 60
(w + x + y + z = 20)
"Mixture of partial esters of fatty acids, mainly stearic acid , with sorbitol and its anhydrides, which are ethoxylated with about 20 moles of ethylene oxide for every mole of sorbitol and sorbitol anhydride."
General
Surname Polysorbate 60
other names
  • Tween® 60 ( trade name )
  • Polyoxyethylene (20) sorbitan monostearate ( IUPAC )
  • E  435
Molecular formula C 64 H 126 O 26 (approx)
Brief description

dark yellow, viscous liquid

External identifiers / databases
CAS number 9005-67-8
EC number 500-020-4
ECHA InfoCard 100.105.530
Wikidata Q2103104
properties
Molar mass 1311.7 g mol −1 (approximate)
safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Polysorbate 60 is a surface-active substance that is used as an emulsifier and wetting agent in foods and pharmaceuticals, for example.

properties

The derivative of sorbitol as a complex compound with fatty acids (mainly stearic acid 50) and ethylene oxide is produced in a multi-stage process from usually vegetable fats. Polysorbate 60 has an HLB value of 14.9 and is therefore suitable for the production of oil-in-water emulsions. The emulsifying effect is strong and independent of acidity and temperature.

use

Polysorbate 60 is approved in the EU as a food additive with the number E 435 for certain foods in quantities of up to five, in shortening also up to ten grams per kilogram and in food supplements without maximum quantity restrictions ( quantum satis ). The permitted daily dose is 10 milligrams per kilogram of body weight for all polysorbates combined. It acts as an emulsifier, foaming agent and complexing agent.

Polysorbates are metabolized in the human organism like fatty acids and are biodegraded in nature like natural fat.

See also

Other representatives from the group of polysorbates are:

Individual evidence

  1. ↑ European Pharmacopoeia , Deutscher Apotheker Verlag Stuttgart, 6th edition, 2008, pp. 3720–3721, ISBN 978-3-7692-3962-1 .
  2. ↑ Entry on E 435: Polyoxyethylene sorbitan monostearate (polysorbate 60) in the European database for food additives, accessed on June 27, 2020.
  3. ↑ a b c Datasheet Polysorbate 60 from Sigma-Aldrich , accessed on May 18, 2017 ( PDF ).
  4. ↑ Additives database: Polysorbate 60 .