Eur m 1
| Peptidase 1 | ||
|---|---|---|
| other names |
Allergen Eur m I, Mite group 1 allergen Eur m 1 |
|
| Mass / length primary structure | 321 amino acids in the zymogen , 36,290 Da , 223 amino acids in the active form | |
| Identifier | ||
| External IDs | ||
| Enzyme classification | ||
| EC, category | 3.4.22.65 | |
The Euroglyphus maynei peptidase 1 (Eur m 1) is an enzyme from the group of cysteine proteases and is produced by the Mayne house dust mite Euroglyphus maynei . It is one of the major house dust allergens of the people , as well as its homologues Der p 1 from the European house dust mite Dermatophagoides pteronyssinus and Der f 1 from the American house dust mite Dermatophagoides farinae .
properties
Eur m 1 has the amino acid cysteine in its active center as a cysteine protease . It is an endopeptidase and preferentially hydrolyzes peptides with a hydrophobic or basic amino acid at position P2. The release occurs fecally .
Web links
Individual evidence
- ↑ JC Bessot, G. Pauli: Mite allergens: an overview. In: European annals of allergy and clinical immunology. Volume 43, Number 5, October 2011, pp. 141-156, PMID 22145250 .