Frank Grosveld

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Frank Grosveld

Franklin Gerardus "Frank" Grosveld (born August 18, 1948 ) is a Dutch molecular biologist .

Life

Grosveld studied biochemistry at the University of Amsterdam and received his PhD from McGill University in 1976 . As a post-doctoral student he worked with Charles Weissmann in Zurich and Richard Flavell in London before moving to the National Institute for Medical Research in Great Britain (Mill Hill), where he led his own research group and from 1981 head of the Gene Structure Department and expression was. In 1993 he became Professor of Cell Biology and Genetics at the Erasmus University Rotterdam . In 2008 he became Academy Professor at the Dutch Academy of Sciences.

Grosveld discovered Locus Control Regions (LCR) of genes while studying the gene expression of globins .

While studying the maturation of erythrocytes , he discovered the role of the transcription factor GATA1. He also dealt with DNA methylation and chromatin structure.

In 1995 he won the Spinoza Prize . He is a member of the Royal Netherlands Academy of Sciences (1994) and the Academia Europaea (1989) and Fellow of the Royal Society (1991). In 1991 he received the Louis Jeantet Prize for Medicine and in 1992 the Howard Hughes International Research Scholar Award. In 2013 he became a Knight of the Order of the Dutch Lion. In 1986 he became a member of EMBO . He is the co-founder of four companies.

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