Richard Flavell

from Wikipedia, the free encyclopedia

Richard Anthony Flavell FRS (* 1945 ) is a British molecular biologist .

Life

After schooling studied Flavell at the University of Hull , and then with a Europe - Fellowship of the Royal Society at the University of Amsterdam and later with a PhD scholarship at the University of Zurich . He then worked at the University of Amsterdam between 1973 and 1979, before becoming head of the laboratory for the structure and designation of genes at the National Institute for Medical Research in Mill Hill, London , where he worked until 1982. The Canadian molecular biologist Frank Grosveld, who is now a professor at the Royal Netherlands Academy of Sciences , was one of his colleagues at the time.

He was then President of Biogen Corporation between 1982 and 1988 and was also a Fellow of the Royal Society in 1984 .

1988 Flavell took the offer of a professorship at the Medical Faculty of Yale University and teaches since then there. He is currently Sterling Professor of Immunology there and was also a researcher at the Howard Hughes Medical Institute .

He earned particular renown for his research into the structure of human genes for globins . A particularly important facet of his work was the illustration that in a group of inherited anemias , genetic defects, the complete absence of a particular globin gene, while in other types of this group of diseases, the defect resides at a great distance from the affected gene.

Such work on naturally occurring manipulations is invaluable in the DNA sequencing that regulates globingen control. In addition, the work has been used to demonstrate the role of precise elements of DNA , thereby enabling the introduction of gene therapy as a treatment for aemias.

In 1980 he was awarded the Colworth Medal of the American Association of Immunologists for his research . He has been a Fellow of the American Association for the Advancement of Science since 1999 . He also became a member of the National Academy of Sciences (NAS) in 2002 . For 2012, Flavell was awarded the William B. Coley Award for Distinguished Research in Basic Immunology .

Publications

  • Genome Evolution , co-authored by Gabriel Dover, Academic Press, 1982

swell