Georg-Friedrich Kahl

Georg-Friedrich Kahl (born October 21, 1936 in Potsdam ; † February 1, 2019 in Kleve ) was a German doctor , pharmacologist and toxicologist . He was a professor emeritus at the Georg-August-Universität Göttingen .

Life

Kahl studied human medicine from 1955 to 1961 at the University of Hamburg and the Eberhard Karls University of Tübingen . He was a member of the Corps Irminsul in Hamburg. In 1961 he passed his medical examination and then studied psychology until 1964 . It was in 1966 when Karl Joachim Nice at the Medical Faculty in Hamburg with the pharmacological-toxicological dissertation isolated studies on oxygen consumption peritoneal mast cells of the rat during histamine release by substance 48/80 to Dr. med. PhD. He then worked at the Pharmacological Institutes in Hamburg and Mainz. In 1971 he completed his habilitation under Gustav Kuschinsky at the Johannes Gutenberg University in Mainz . He received the venia legendi in pharmacology and toxicology and in 1985 was offered a C4 professorship at the Georg-August-Universität Göttingen . Up until his retirement in 2002, he was head of the toxicology department in the human medicine department and specialist in clinical pharmacology at the University Hospital Göttingen . He also built the Poison Information Center North for the states of Bremen, Hamburg, Lower Saxony and Schleswig-Holstein.

Kahl was a member of the Society for Toxicological and Forensic Chemistry (GTFCh). He has published numerous articles in journals such as Anticancer Research , Archives of Toxicology , Biochemical and Biophysical Research Communications , Biochemical Journal , Biochemical Pharmacology , Cancer Letters , Carcinogenesis , Deutsche Medizinische Wochenschrift , Drug Metabolism and Disposition , FEBS Letters , Food and Chemical Toxicology , Journal of Biological Chemistry , Journal of Pharmacology and Experimental Therapeutics , Molecular Pharmacology , Naunyn-Schmiedebergs Archiv, and Toxicology and Applied Pharmacology ; his h-index is 22 (as of April 5, 2014).

Publications

The four most cited articles are listed.

• Okey, AB; Bondy, GP; Mason, ME; Kahl, GF; Iron, HJ; Guenthner, TM; Nebert, DW: Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation . In: Journal of Biological Chemistry . Vol. 254, No. 22 , 1979, pp. 11636-11648 .
• Höhne, MW; Halatsch, ME; Kahl, GF; Weinel, RJ: Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma . In: Cancer Research . Vol. 52, No. 9 , 1992, pp. 2616-2619 .
• Ziemann, C; Burkle, A; Kahl, GF; Hirsch-Ernst, KI: Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures . In: Carcinogenesis . Vol. 20, No. 3 , 1999, p. 407-414 , doi : 10.1093 / carcin / 20.3.407 .
• Netter, KJ; Kahl, GF; Magnussen, MP: Kinetic experiments on the binding of metyrapone to liver microsomes . In: Naunyn-Schmiedebergs Archive for Pharmacology . Vol. 265, No. 3 , 1969, p. 205-215 , doi : 10.1007 / BF01002335 .

literature

• Athineos Philippu : History and work of the pharmacological, clinical-pharmacological and toxicological institutes in German-speaking countries . Volume 1, Berenkamp, ​​Innsbruck 2004, ISBN 3-85093-180-3 , p. 487.

Web links

• Publications by Georg-Friedrich Kahl in the PubMed medical database

Individual evidence

1. ^ Giftinformationszentrum-Nord celebrates its 10th anniversary ( memento of 7 April 2014 in the Internet Archive ), press release from GIZ-Nord, No. 137, 20 September 2006.
2. ↑ Personalia 2001 , GTFCh, accessed on April 5, 2014.
3. ↑ ^{a b} Web of Science Search. In: Web of Science . Thomson Reuters , accessed April 6, 2014 .